# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5121010 | Binding | Inhibition of recombinant human N-terminal His6-SUMO-tagged C-terminal SII-tagged HDAC4 expressed in Escherichia coli (BL21) DE3 pLysS cells assessed as residual activity at 50 uM using BocLys(trifluoroacetyl)-AMC as substrate incubated for 30 mins by fluorescence assay relative to control | Homo sapiens | 19 | ALA5120742 | cell-based format | Scientific Literature | |
2. | ALA5121011 | Binding | Inhibition of recombinant human N-terminal His6-SUMO-tagged C-terminal SII-tagged HDAC8 expressed in Escherichia coli (BL21) DE3 pLysS cells assessed as residual activity at 50 uM using BocLys(trifluoroacetyl)-AMC as substrate incubated for 30 mins by fluorescence assay relative to control | Homo sapiens | 19 | ALA5120742 | cell-based format | Scientific Literature | |
3. | ALA5121012 | Binding | Inhibition of recombinant human N-terminal His6-SUMO-tagged C-terminal SII-tagged HDAC4 expressed in Escherichia coli (BL21) DE3 pLysS cells using BocLys(trifluoroacetyl)-AMC as substrate incubated for 30 mins by fluorescence assay | Homo sapiens | 19 | ALA5120742 | cell-based format | Scientific Literature | |
4. | ALA5121013 | Binding | Inhibition of recombinant human N-terminal His6-SUMO-tagged C-terminal SII-tagged HDAC8 expressed in Escherichia coli (BL21) DE3 pLysS cells using BocLys(trifluoroacetyl)-AMC as substrate incubated for 30 mins by fluorescence assay | Homo sapiens | 19 | ALA5120742 | cell-based format | Scientific Literature |