| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5160364 | A | AUC(0 to t) in Beagle dog at 26.76 mg/kg, iv administered as single dose measured up to 24 hrs | Canis lupus familiaris | 1 | organism-based format | Scientific Literature | ||
| 2. | ALA5160365 | A | AUCextra in C57BL/6J mouse at 9.103 mg/kg, ip administered as single dose measured up to 24 hrs | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 3. | ALA5160366 | T | Toxicity in C57BL/6 mouse assessed as change in body weight at 50 mg/kg, ip administered as single dose and measured after 15 days (Rvb = 23.5 to 24.2 g) | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 4. | ALA5160367 | T | Toxicity in C57BL/6 mouse assessed as change in body weight at 100 mg/kg, ip administered as single dose and measured after 15 days (Rvb = 23.5 to 24.2 g) | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 5. | ALA5160368 | T | Toxicity in C57BL/6 mouse assessed as change in liver weight at 50 mg/kg, ip administered as single dose and measured after 15 days (Rvb = 1.2 to 1.3 g) | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 6. | ALA5160369 | T | Toxicity in C57BL/6 mouse assessed as change in liver weight at 500 mg/kg, ip administered as single dose and measured after 15 days (Rvb = 1.2 to 1.3 g) | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 7. | ALA5160370 | T | Toxicity in C57BL/6 mouse assessed as change in spleen weight at 500 mg/kg, ip administered as single dose and measured after 15 days (Rvb = 0.1 to 0.2 g) | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 8. | ALA5160371 | T | Toxicity in C57BL/6 mouse assessed as change in kidney weight at 100 mg/kg, ip administered as single dose and measured after 15 days (Rvb = 0.3 g) | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 9. | ALA5160372 | F | Antitumour activity against mouse wild type MCA-205 cells implanted in C57BL/6 mouse assessed as tumor size by measuring cell killing pretreatment at 2.5 mg/kg, iv administered starting from day 7 post inoculation at five days interval upto 17 days relative to control | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 10. | ALA5160373 | F | Antiproliferative activity against human MCF7 cells assessed as growth inhibition at 10 uM measured after 72 hrs by MTT based colorimetric assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA5160374 | F | Antiproliferative activity against human A549 cells assessed as growth inhibition at 10 uM measured after 72 hrs by MTT based colorimetric assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA5160375 | F | Antiproliferative activity against human HCT-116 cells assessed as growth inhibition at 10 uM measured after 72 hrs by MTT based colorimetric assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA5160376 | F | Antiproliferative activity against human K562 cells assessed as growth inhibition at 10 uM measured after 72 hrs by MTT based colorimetric assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA5160377 | F | Antiproliferative activity against human K-562R cells assessed as growth inhibition at 10 uM measured after 72 hrs by MTT based colorimetric assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA5160378 | F | Antiproliferative activity against mouse MCA-205 cells assessed as decrease in cell viability at 10 uM measured after 72 hrs by MTT based colorimetric assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA5160379 | F | Antiproliferative activity against human HUVEC cells assessed as decrease in cell viability at 10 uM measured after 72 hrs by MTT based colorimetric assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA5160381 | F | Induction of B3Z T-cell activation cocultured with mouse MCA-205 cells expressing SL8 epitope assessed as increase in intron-derived SL8 antigen presentation at 35 uM | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA5160382 | A | Metabolic stability in mouse liver microsomes assessed as parent compound remaining incubated for 45 mins in presence of NADPH by HPLC-MS/MS analysis | Mus musculus | 1 | microsome format | Scientific Literature | ||
| 19. | ALA5160383 | A | Metabolic stability in human liver microsomes assessed as parent compound remaining incubated for 45 mins in presence of NADPH by HPLC-MS/MS analysis | Homo sapiens | 1 | microsome format | Scientific Literature | ||
| 20. | ALA5160384 | A | Metabolic stability in mouse liver microsomes assessed as parent compound remaining incubated for 45 mins in absence of NADPH by HPLC-MS/MS analysis | Mus musculus | 1 | microsome format | Scientific Literature |
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