# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5106912 | F | Activation of human ACKR3 overexpressed in CHO-K1 cells assessed as induction of beta-arrestin recruitment incubated for 90 mins by luminescence based assay | Homo sapiens | 31 | cell-based format | Scientific Literature | ||
2. | ALA5106913 | F | Activation of human C-terminal ACKR3 transfected in HEK293T cells co-transfected with beta arrestin-1 assessed as induction of beta-arrestin recruitment at 300 nM by Nanoluc-complementation assay relative to CXCL12 | Homo sapiens | 31 | cell-based format | Scientific Literature | ||
3. | ALA5106914 | F | Induction of platelet degranulation activity in human peripheral platelet rich plasma assessed as reduction in P-selectin expression at 100 uM pretreated for 15 min followed by CRP-XL treatment and measured after 30 mins by flow cytometry relative to control | Homo sapiens | 19 | cell-free format | Scientific Literature | ||
4. | ALA5106917 | A | Metabolic stability in mouse liver microsomes assessed as compound remaining preincubated for 5 mins with NADPH regenerating system followed by compound addition and measured upto 120 mins by LC-MS analysis | Mus musculus | 2 | microsome format | Scientific Literature | ||
5. | ALA5106918 | A | Metabolic stability in human liver microsomes preincubated for 5 mins with NADPH regenerating system followed by compound addition and measured upto 120 mins by LC-MS analysis | Homo sapiens | 3 | microsome format | Scientific Literature |