# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5134924 | B | Negative allosteric modulation activity at human P2X4 receptor expressed in human 1321N1 cells assessed as ATP induced calcium response by measuring ATP EC50 at 40 nM | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
2. | ALA5134925 | F | Cytotoxicity against human 1321N1 cells assessed as reduction in cell viability at 50 uM incubated for 24 hrs by MTT assay relative to control | Homo sapiens | 22 | cell-based format | Scientific Literature | ||
3. | ALA5134926 | T | Cytotoxicity against human HEK293 cells assessed as reduction in cell viability at 50 uM incubated for 24 hrs by MTT assay relative to control | Homo sapiens | 22 | cell-based format | Scientific Literature | ||
4. | ALA5134927 | F | Cytotoxicity against human HeLa cells assessed as reduction in cell viability at 50 uM incubated for 24 hrs by MTT assay relative to control | Homo sapiens | 22 | cell-based format | Scientific Literature | ||
5. | ALA5134936 | B | Negative allosteric modulation activity at human P2X4 receptor expressed in human 1321N1 cells assessed as ATP induced calcium response by measuring ATP EC50 at 100 nM | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
6. | ALA5134937 | B | Negative allosteric modulation activity at human P2X4 receptor expressed in human 1321N1 cells assessed as ATP induced calcium response by measuring ATP EC50 at 200 nM | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
7. | ALA5134941 | B | Negative allosteric modulation activity at human P2X4 receptor expressed in human 1321N1 cells assessed as ATP induced calcium response by measuring maximal ATP efficacy at 40 nM relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
8. | ALA5134942 | B | Negative allosteric modulation activity at human P2X4 receptor expressed in human 1321N1 cells assessed as ATP induced calcium response by measuring maximal ATP efficacy at 100 nM relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
9. | ALA5134943 | B | Negative allosteric modulation activity at human P2X4 receptor expressed in human 1321N1 cells assessed as ATP induced calcium response by measuring maximal ATP efficacy at 200 nM relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
10. | ALA5134951 | B | Negative allosteric modulation activity at human P2X2 receptor expressed in human 1321N1 cells assessed as reduction in intracellular Ca2+ influx incubated for 30 mins by Fura-2 AM based fluorescence assay relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
11. | ALA5134953 | B | Negative allosteric modulation activity at human P2X4 receptor expressed in human 1321N1 cells assessed as reduction in intracellular Ca2+ influx incubated for 30 mins by Fura-2 AM based fluorescence assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
12. | ALA5134954 | B | Negative allosteric modulation activity at human P2X5 receptor expressed in human 1321N1 cells assessed as reduction in intracellular Ca2+ influx incubated for 30 mins by Fura-2 AM based fluorescence assay relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
13. | ALA5134955 | B | Negative allosteric modulation activity at human P2X7 receptor expressed in human 1321N1 cells assessed as reduction in intracellular Ca2+ influx incubated for 30 mins by Fura-2 AM based fluorescence assay | Homo sapiens | 2 | cell-based format | Scientific Literature |