# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5123995 | F | Antileishmanial activity against intracellular Leishmania infantum MHOM/MA(BE)/67 ITMAP263 amastigotes infected in Swiss mouse peritoneal macrophage assessed as inhibition of parasite growth measured after 5 days by geimsa staining based microscopic analysis | Leishmania infantum | 46 | organism-based format | Scientific Literature | ||
2. | ALA5123996 | T | Cytotoxicity against Swiss mouse peritoneal macrophages assessed as reduction in cell viability measured after 5 days by microscopic analysis | Mus musculus | 46 | cell-based format | Scientific Literature | ||
3. | ALA5123997 | T | Selectivity index, ratio of CC50 for Cytotoxicity against Swiss mouse peritoneal macrophages to EC50 for intracellular Leishmania infantum MHOM/MA(BE)/67 ITMAP263 amastigotes infected in Swiss mouse peritoneal macrophages | 45 | cell-based format | Scientific Literature | |||
4. | ALA5123998 | T | Cytotoxicity against human MRC5 cells assessed as reduction in cell viability incubated for 3 days by resazurin dye based fluorescence analysis | Homo sapiens | 39 | cell-based format | Scientific Literature | ||
5. | ALA5124002 | F | Antitrypanosomal activity against nifurtimox-sensitive Tulahuen CL2 amastigotes expressing beta galactosidase infected in human MRC5 cells assessed as inhibition of parasite growth using chlorophenol red beta-D-galactopyranoside as substrate and measured after 7 days by spectrophotometric analysis | Trypanosoma cruzi | 12 | organism-based format | Scientific Literature | ||
6. | ALA5124011 | T | Selectivity index, ratio of CC50 for cytotoxicity against human MRC5 cells to EC50 for Trypanosoma cruzi Tulahuen CL2 amastigotes expressing beta galactosidase infected in human MRC5 cells | 12 | cell-based format | Scientific Literature |