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# Aladdin ID Assay Type Description Organism Compounds Reference BAO Format Source 1. ALA5112808 A Apparent permeability of the compound across apical side to basolateral side in human Caco-2 cells incubated for 1 hr by LC-MS/MS analysis Homo sapiens 21 cell-based format Scientific Literature 2. ALA5112809 B Inhibition of human plasma kallikrein using H-D-Pro-Phe-Arg-AFC as flurogenic substrate preincubated for 5 mins followed by substrate addition by fluorometer analysis Homo sapiens 82 cell-free format Scientific Literature 3. ALA5112810 A Metabolic stability in human liver microsomes assessed as intrinsic clearance per mg of protein measured upto 60 mins in presence of NADPH regenerating system by LC-MS/MS analysis Homo sapiens 21 microsome format Scientific Literature 4. ALA5112817 P Thermodynamic solubility of the compound in FaSSIF at 1 mg/ml at pH 6.5 measured after 4 hrs 4 small-molecule physicochemical format Scientific Literature 5. ALA5112818 P Thermodynamic solubility of the compound in FaSSGF at 1 mg/ml at pH 1.6 measured after 4 hrs 4 small-molecule physicochemical format Scientific Literature 6. ALA5112820 A Clearance in Sprague-Dawley rat plasma at 1 mg/kg, iv measured upto 24 hrs by LC-MS analysis Rattus norvegicus 5 organism-based format Scientific Literature 7. ALA5112821 A Clearance in Beagle dog plasma at 1 mg/kg, iv measured upto 24 hrs by LC-MS analysis Canis lupus familiaris 3 organism-based format Scientific Literature 8. ALA5112822 A Clearance in Sprague-Dawley rat blood at 1 mg/kg, iv measured upto 24 hrs by LC-MS analysis Rattus norvegicus 5 organism-based format Scientific Literature 9. ALA5112823 A Clearance in Beagle dog blood at 1 mg/kg, iv measured upto 24 hrs by LC-MS analysis Canis lupus familiaris 3 organism-based format Scientific Literature 10. ALA5112824 A Clearance in Sprague-Dawley rat assessed as liver blood flow at 1 mg/kg, iv measured upto 24 hrs by LC-MS analysis Rattus norvegicus 5 organism-based format Scientific Literature 11. ALA5112825 A Clearance in Beagle dog assessed as liver blood flow at 1 mg/kg, iv measured upto 24 hrs by LC-MS analysis Canis lupus familiaris 3 organism-based format Scientific Literature 12. ALA5112826 A Volume of distribution at steady state in Sprague-Dawley rat at 10 mg/kg, po and 1 mg/kg, iv measured upto 24 hrs by LC-MS analysis Rattus norvegicus 5 organism-based format Scientific Literature 13. ALA5112827 A Volume of distribution at steady state in Beagle dog at 1 mg/kg, po and 1 mg/kg, iv measured upto 24 hrs by LC-MS analysis Canis lupus familiaris 3 organism-based format Scientific Literature 14. ALA5112828 A Half life in Sprague-Dawley rat at 10 mg/kg, po and 1 mg/kg, iv measured upto 24 hrs by LC-MS analysis Rattus norvegicus 5 organism-based format Scientific Literature 15. ALA5112829 A Half life in Beagle dog at 1 mg/kg, po and 1 mg/kg, iv measured upto 24 hrs by LC-MS analysis Canis lupus familiaris 3 organism-based format Scientific Literature 16. ALA5112830 A Oral bioavailability in Sprague-Dawley rat at 10 mg/kg measured upto 24 hrs by LC-MS analysis Rattus norvegicus 5 organism-based format Scientific Literature 17. ALA5112831 A Oral bioavailability in Beagle dog at 1 mg/kg measured upto 24 hrs by LC-MS analysis Canis lupus familiaris 3 organism-based format Scientific Literature 18. ALA5112832 T Inhibition of hERG expressed in CHO cells by whole cell patch clamp assay Homo sapiens 3 cell-based format Scientific Literature 19. ALA5112833 A Inhibition of CYP1A2 in human liver microsomes assessed as reduction in acetaminophen metabolite formation incubated for 30 mins in presence of NADPH by LC-MS/MS analysis Homo sapiens 3 microsome format Scientific Literature 20. ALA5112834 A Inhibition of CYP2B6 in human liver microsomes assessed as reduction in hydroxybupropion metabolite formation incubated for 30 mins in presence of NADPH by LC-MS/MS analysis Homo sapiens 3 microsome format Scientific Literature