# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5144094 | Binding | Inhibition of ASF1a phosphorylation at S166 residue in human MDA-MB-231 cells at 10 uM incubated for 4 hrs by Western blot analysis | Homo sapiens | 8 | ALA5143513 | cell-based format | Scientific Literature | |
2. | ALA5144095 | Binding | Inhibition of full length FLAG/HA/Strep-tagged TLK2 (unknown origin) transfected in HEK293T cells assessed as reduction in ASF1a phosphorylation at S166 residue at 5 uM by Western blot analysis | Homo sapiens | 5 | ALA5143513 | cell-based format | Scientific Literature | |
3. | ALA5144096 | Functional | Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability at 0.5 uM measured after 72 hrs by MTT assay | Homo sapiens | 8 | ALA5143513 | cell-based format | Scientific Literature | |
4. | ALA5144097 | Binding | Binding affinity to full length FLAG/HA/Strep-tagged TLK2 (388 to 772 residues) (unknown origin) transfected in HEK293T cells by Alexa Fluor 647 staining based FRET assay | Homo sapiens | 3 | ALA5143513 | cell-based format | Scientific Literature | |
5. | ALA5144098 | Functional | Effect on cell cycle progression in human MDA-MB-231 cells assessed as accumulation of cells at S phase at 4 uM by PI staining based flow cytometric analysis | Homo sapiens | 4 | ALA5143513 | cell-based format | Scientific Literature | |
6. | ALA5144099 | Functional | Effect on cell cycle progression in human MDA-MB-231 cells assessed as accumulation of cells at S phase at 2 uM by PI staining based flow cytometric analysis | Homo sapiens | 3 | ALA5143513 | cell-based format | Scientific Literature | |
7. | ALA5144100 | Functional | Induction of DNA damage in human MDA-MB-231 cells at 10 uM incubated for 4 hrs by gel electrophoresis method | Homo sapiens | 4 | ALA5143513 | cell-based format | Scientific Literature | |
8. | ALA5144101 | Functional | Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell growth at 0.25 uM by trypan blue assay | Homo sapiens | 2 | ALA5143513 | cell-based format | Scientific Literature | |
9. | ALA5144102 | Functional | Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell growth at 1 uM by trypan blue assay | Homo sapiens | 1 | ALA5143513 | cell-based format | Scientific Literature | |
10. | ALA5144103 | Functional | Antiproliferative activity against human MDA-MB-231 cells assessed as increase in cell death rate at 1 uM by trypan blue assay | Homo sapiens | 1 | ALA5143513 | cell-based format | Scientific Literature | |
11. | ALA5144104 | Functional | Induction of cell cycle arrest in human MDA-MB-231 cells assessed as increase in cells at sub G1 phase at 2 uM measured after 72 hrs by PI staining based flow cytometric analysis (Rvb = 0.8%) | Homo sapiens | 1 | ALA5143513 | cell-based format | Scientific Literature | |
12. | ALA5144105 | Functional | Induction of cell cycle arrest in human MDA-MB-231 cells assessed as increase in cells at sub G1 phase at 4 uM measured after 72 hrs by PI staining based flow cytometric analysis (Rvb = 0.8%) | Homo sapiens | 1 | ALA5143513 | cell-based format | Scientific Literature | |
13. | ALA5144106 | Functional | Induction of apoptosis in human MDA-MB-231 cells assessed as increase in caspase-3 level at 4 uM incubated for 72 hrs by gel electrophoresis method | Homo sapiens | 1 | ALA5143513 | cell-based format | Scientific Literature | |
14. | ALA5144107 | Functional | Induction of apoptosis in human MDA-MB-231 cells assessed as increase in caspase-9 level at 4 uM incubated for 72 hrs by gel electrophoresis method | Homo sapiens | 1 | ALA5143513 | cell-based format | Scientific Literature | |
15. | ALA5144108 | Functional | Induction of apoptosis in human MDA-MB-231 cells assessed as decrease in Bcl-xL level at 4 uM incubated for 72 hrs by gel electrophoresis method | Homo sapiens | 1 | ALA5143513 | cell-based format | Scientific Literature | |
16. | ALA5144109 | Functional | Induction of apoptosis in human MDA-MB-231 cells assessed as decrease in MCL-1 level at 4 uM incubated for 72 hrs by gel electrophoresis method | Homo sapiens | 1 | ALA5143513 | cell-based format | Scientific Literature | |
17. | ALA5144110 | Functional | Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay | Homo sapiens | 5 | ALA5143513 | cell-based format | Scientific Literature | |
18. | ALA5144111 | Functional | Cytotoxicity against human A549 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay | Homo sapiens | 5 | ALA5143513 | cell-based format | Scientific Literature | |
19. | ALA5144112 | Functional | Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay | Homo sapiens | 5 | ALA5143513 | cell-based format | Scientific Literature | |
20. | ALA5144113 | Toxicity | Cytotoxicity against human IMR-90 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay | Homo sapiens | 5 | ALA5143513 | cell-based format | Scientific Literature |