| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5112649 | B | Binding affinity to 15N-labeled recombinant human PBRM1 BD2 transfected in Escherichia coli BL21 (DE3) assessed as thermal stabilization by measuring change in melting temperature at 100 uM by SYPRO orange dye based differential scanning fluorimetry analysis | Homo sapiens | 40 | assay format | Scientific Literature | ||
| 2. | ALA5112650 | B | Inhibition of biotinylated histone H3K14 (1 to 20 residues) peptide binding to His6-tagged recombinant human PBRM1 BD2 transfected in Escherichia coli BL21 (DE3) incubated for 30 mins by Alphascreen assay | Homo sapiens | 32 | assay format | Scientific Literature | ||
| 3. | ALA5112651 | B | Binding affinity to His-TEV-tagged recombinant human PBRM1 BD2 transfected in Escherichia coli BL21 (DE3) assessed as dissociation constant at 30 uM by ITC analysis | Homo sapiens | 7 | assay format | Scientific Literature | ||
| 4. | ALA5112653 | B | Binding affinity to His-TEV-tagged human PBRM1 BD5 transfected in Escherichia coli BL21 (DE3) assessed as dissociation constant at 30 uM by ITC analysis | Homo sapiens | 7 | assay format | Scientific Literature | ||
| 5. | ALA5112654 | B | Binding affinity to N-terminal His6-TEV-tagged human SMARCA2B transfected in Escherichia coli BL21 (DE3) assessed as dissociation constant at 30 uM by ITC analysis | Homo sapiens | 4 | assay format | Scientific Literature | ||
| 6. | ALA5112655 | B | Binding affinity to N-terminal His-TEV-tagged human SMARCA4 transfected in Escherichia coli BL21 (DE3) assessed as dissociation constant at 30 uM by ITC analysis | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 7. | ALA5112671 | F | Cytotoxicity against human LNCaP cells assessed as inhibition of cell growth at 10 uM measured after 7 days with compound replacement for every 48 hrs by celltiter-glo assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 8. | ALA5112700 | B | Binding affinity to N-terminal His-TEV-tagged human ASH1L expressed in transfected in Escherichia coli BL21 (DE3) at 30 uM by ITC analysis | Homo sapiens | 3 | assay format | Scientific Literature |
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