# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5096975 | B | Inhibition of N-terminal 6His-tagged full-length H2N-VE(pY)LDLDLD(PEG8)RVD(pY)VVVDQQ-amide-activated SHP2 (247 to 529 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) using DiFMUP as substrate preincubated for 10 to 30 mins with activating peptide prior to compound addition for 30 mins followed by substrate addition and measured for 6 mins by fluorescence based assay | Homo sapiens | 2 | ALA5096160 | assay format | Scientific Literature | |
2. | ALA5096987 | F | Cytotoxicity against human SW1463 cells assessed as inhibition of cell growth incubated for 120 hrs by MTT assay | Homo sapiens | 1 | ALA5096160 | cell-based format | Scientific Literature | |
3. | ALA5096990 | B | Inhibition of SHP2 in human LS180 cells | Homo sapiens | 1 | ALA5096160 | cell-based format | Scientific Literature |