# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5139979 | Functional | Antiviral activity against HSV-2 333vhsB infected in African green monkey Vero cells assessed as inhibition of viral replication by measuring reduction in virus-induced cytopathic effect at 50 uM incubated for 20 hrs by colorimetric analysis | Human alphaherpesvirus 2 | 44 | ALA5137030 | organism-based format | Scientific Literature | |
2. | ALA5139980 | Functional | Antiviral activity against HSV-2 infected in African green monkey Vero cells assessed as inhibition of viral replication by measuring log suppression of virus-induced cytopathic effect at 5 uM incubated for 1 hr followed by washing with PBS and subsequent treatment with compound for 24 hrs by plaque assay | Human alphaherpesvirus 2 | 46 | ALA5137030 | organism-based format | Scientific Literature | |
3. | ALA5139981 | Functional | Antiviral activity against HSV-2 infected in African green monkey Vero cells assessed as inhibition of viral replication by measuring log suppression of virus-induced cytopathic effect at 1 uM incubated for 1 hr followed by washing with PBS and subsequent treatment with compound for 24 hrs by plaque assay | Human alphaherpesvirus 2 | 46 | ALA5137030 | organism-based format | Scientific Literature | |
4. | ALA5139985 | Functional | Antiviral activity against HSV-2 infected in African green monkey Vero cells assessed as inhibition of viral replication incubated for 1 hr followed by washing with PBS and subsequent treatment with compound for 24 hrs by plaque reduction assay | Human alphaherpesvirus 2 | 20 | ALA5137030 | organism-based format | Scientific Literature | |
5. | ALA5139986 | Toxicity | Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability incubated for 24 hrs by MTS assay | Chlorocebus sabaeus | 20 | ALA5137030 | cell-based format | Scientific Literature | |
6. | ALA5139987 | Toxicity | Cytotoxicity against human HepDES19 cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay | Homo sapiens | 19 | ALA5137030 | cell-based format | Scientific Literature | |
7. | ALA5139988 | Toxicity | Selectivity index, ratio of CC50 for cytotoxicity against African green monkey Vero cells to EC50 for antiviral activity against HSV-2 infected in African green monkey Vero cells | 20 | ALA5137030 | cell-based format | Scientific Literature | ||
8. | ALA5139989 | Toxicity | Selectivity index, ratio of CC50 for cytotoxicity against human HepDES19 cells to EC50 for antiviral activity against HSV-2 infected in African green monkey Vero cells | 19 | ALA5137030 | cell-based format | Scientific Literature |