| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5108746 | F | Antiviral activity against Ebola infected in human macrophages assessed as reduction in viral replication | Ebolavirus | 2 | organism-based format | Scientific Literature | ||
| 2. | ALA5108747 | F | Potency index, ratio of EC50 of GS-441524 to EC50 of test compound for antiviral activity against Ebola infected in human macrophages assessed as reduction in viral replication | Ebolavirus | 1 | organism-based format | Scientific Literature | ||
| 3. | ALA5108748 | F | Antiviral activity against Ebola infected in human HeLa cells assessed as reduction in viral replication | Ebolavirus | 2 | organism-based format | Scientific Literature | ||
| 4. | ALA5108749 | F | Potency index, ratio of EC50 of GS-441524 to EC50 of test compound for antiviral activity against Ebola infected in human HeLa cells assessed as reduction in viral replication | Ebolavirus | 1 | organism-based format | Scientific Literature | ||
| 5. | ALA5108750 | F | Antiviral activity against MARV Rec. Bat371-GFP infected in human Huh-7 cells assessed as reduction in viral replication incubated for 48 to 144 hrs by fluorescence based assay | Marburgvirus | 2 | organism-based format | Scientific Literature | ||
| 6. | ALA5108751 | F | Potency index, ratio of EC50 of GS-441524 to EC50 of test compound for antiviral activity against MARV Rec. Bat371-GFP infected in human Huh-7 cells assessed as reduction in viral replication incubated for 48 to 144 hrs by fluorescence based assay | Marburgvirus | 1 | organism-based format | Scientific Literature | ||
| 7. | ALA5108752 | F | Antiviral activity against Nipah M1999 infected in human HeLa cells assessed as reduction in viral replication incubated for 48 to 144 hrs by reporter virus assay | Henipavirus nipahense | 2 | organism-based format | Scientific Literature | ||
| 8. | ALA5108753 | F | Potency index, ratio of EC50 of GS-441524 to EC50 of test compound for antiviral activity against Nipah M1999 infected in human HeLa cells assessed as reduction in viral replication incubated for 48 to 144 hrs by reporter virus assay | Henipavirus nipahense | 1 | organism-based format | Scientific Literature | ||
| 9. | ALA5108754 | F | Antiviral activity against Nipah B2004 infected in human NCI-H358 cells assessed as reduction in viral replication incubated for 48 to 144 hrs by reporter virus assay | Henipavirus nipahense | 2 | organism-based format | Scientific Literature | ||
| 10. | ALA5108755 | F | Potency index, ratio of EC50 of GS-441524 to EC50 of test compound for antiviral activity against Nipah B2004 infected in human NCI-H358 cells assessed as reduction in viral replication incubated for 48 to 144 hrs by reporter virus assay | Henipavirus nipahense | 1 | organism-based format | Scientific Literature | ||
| 11. | ALA5108756 | F | Antiviral activity against Measles Rec.rMVEZGFP(3) infected in human HeLa cells assessed as reduction in viral replication incubated for 48 to 144 hrs by fluorescence based assay | Measles morbillivirus | 2 | organism-based format | Scientific Literature | ||
| 12. | ALA5108757 | F | Potency index, ratio of EC50 of GS-441524 to EC50 of test compound for antiviral activity against Measles Rec.rMVEZGFP(3) infected in human HeLa cells assessed as reduction in viral replication incubated for 48 to 144 hrs by fluorescence based assay | Measles morbillivirus | 1 | organism-based format | Scientific Literature | ||
| 13. | ALA5108758 | F | Antiviral activity against Measles virus infected in HMVEC cells assessed as reduction in viral replication | Measles morbillivirus | 2 | organism-based format | Scientific Literature | ||
| 14. | ALA5108759 | F | Potency index, ratio of EC50 of GS-441524 to EC50 of test compound for antiviral activity against Measles virus infected in HMVEC cells assessed as reduction in viral replication | Measles morbillivirus | 1 | organism-based format | Scientific Literature | ||
| 15. | ALA5108760 | F | Antiviral activity against SARS-CoV infected in HAE cells assessed as reduction in viral replication at MOI of 0.5 preincubated for 3 hrs followed by virus removal measured after 48 hrs by Hoechst 33258 staining based assay | Severe acute respiratory syndrome-related coronavirus | 2 | organism-based format | Scientific Literature | ||
| 16. | ALA5108761 | F | Potency index, ratio of EC50 of GS-441524 to EC50 of test compound for antiviral activity against SARS-CoV infected in HAE cells assessed as reduction in viral replication at MOI of 0.5 preincubated for 3 hrs followed by virus removal measured after 48 hrs by Hoechst 33258 staining based assay | Severe acute respiratory syndrome-related coronavirus | 1 | organism-based format | Scientific Literature | ||
| 17. | ALA5108762 | F | Antiviral activity against SARS-CoV-2 infected in human A549 cells expressing hACE2 assessed as reduction in viral replication at MOI of 0.025 incubated for 48 hrs by luciferase based assay | Severe acute respiratory syndrome coronavirus 2 | 2 | organism-based format | Scientific Literature | ||
| 18. | ALA5108763 | F | Potency index, ratio of EC50 of GS-441524 to EC50 of test compound for antiviral activity against SARS-CoV-2 infected in human A549 cells expressing hACE2 assessed as reduction in viral replication at MOI of 0.025 incubated for 48 hrs by luciferase based assay | Severe acute respiratory syndrome coronavirus 2 | 1 | organism-based format | Scientific Literature | ||
| 19. | ALA5108764 | F | Antiviral activity against SARS-CoV-2 infected in HAEC cells assessed as reduction in viral replication incubated for 1.5 hrs followed by virus removal upto 24 hrs and subsequent replacement of medium containing compound by RT-qPCR analysis | Severe acute respiratory syndrome coronavirus 2 | 2 | organism-based format | Scientific Literature | ||
| 20. | ALA5108765 | F | Potency index, ratio of EC50 of GS-441524 to EC50 of test compound for antiviral activity against SARS-CoV-2 infected in HAEC cells assessed as reduction in viral replication incubated for 1.5 hrs followed by virus removal upto 24 hrs and subsequent replacement of medium containing compound by RT-qPCR analysis | Severe acute respiratory syndrome coronavirus 2 | 1 | organism-based format | Scientific Literature |
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