| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5123331 | F | Anti-inflammatory activity against mouse RAW264.7 cells assessed as inhibition of LPS-induced NO production at 25 uM incubated for 16 hrs by Greiss reagent assay | Mus musculus | 2 | ALA5120844 | cell-based format | Scientific Literature | |
| 2. | ALA5123332 | T | Cytotoxicity against mouse RAW264.7 cells assessed as reduction in cell viability at 25 uM incubated for 48 hrs by MTT assay | Mus musculus | 1 | ALA5120844 | cell-based format | Scientific Literature | |
| 3. | ALA5123333 | B | Inhibition of NF-kappaB transcriptional activity in human HeLa cells transfected with NF-kappaB-Luc at 10 uM by dual-luciferase reporter gene assay relative to control | Homo sapiens | 14 | ALA5120844 | cell-based format | Scientific Literature | |
| 4. | ALA5123334 | B | Binding affinity to recombinant human GST-tagged glucocorticoid receptor ligand binding domain at 10 uM by TR-FRET assay relative to control | Homo sapiens | 1 | ALA5120844 | single protein format | Scientific Literature | |
| 5. | ALA5123335 | B | Binding affinity to recombinant human GST-tagged glucocorticoid receptor ligand binding domain by TR-FRET assay relative to control | Homo sapiens | 1 | ALA5120844 | single protein format | Scientific Literature | |
| 6. | ALA5123336 | B | Transactivation at glucocorticoid receptor in human HeLa-MMTV-Luc cells incubated for 18 hrs by firefly luciferase assay | Homo sapiens | 1 | ALA5120844 | cell-based format | Scientific Literature | |
| 7. | ALA5123337 | B | Induction of glucocorticoid receptor nuclear translocation in human A549 cells incubated for 2 hrs by confocal microscopic analysis | Homo sapiens | 3 | ALA5120844 | cell-based format | Scientific Literature | |
| 8. | ALA5123338 | F | Anti-inflammatory activity against human A549 cells assessed as reduction in TNFalpha induced IL-1beta mRNA expression level by qRT-PCR analysis | Homo sapiens | 2 | ALA5120844 | cell-based format | Scientific Literature | |
| 9. | ALA5123339 | F | Anti-inflammatory activity against human A549 cells transfected with siGR assessed as reduction in TNFalpha induced IL-1beta mRNA expression level by qRT-PCR analysis | Homo sapiens | 1 | ALA5120844 | cell-based format | Scientific Literature | |
| 10. | ALA5123340 | B | Agonist activity at progesterone receptor (unknown origin) expressed in PC3 cells co-transfected with ARR3tk-luciferase/Renilla at 10 to 25 uM incubated for 16 hrs by luciferase reporter gene assay | Homo sapiens | 2 | ALA5120844 | cell-based format | Scientific Literature | |
| 11. | ALA5123341 | B | Agonist activity at mineralocorticoid receptor (unknown origin) expressed in HEK293T cells co-transfected with pGL4.36[luc2P MMTV Hygro]/Renilla at 10 to 25 uM incubated for 16 hrs by luciferase reporter gene assay | Homo sapiens | 2 | ALA5120844 | cell-based format | Scientific Literature | |
| 12. | ALA5123342 | F | Induction of osteoporosis in human MG-63 cells assessed as decrease in OPG mRNA expression level at 10 uM by qRT-PCR analysis | Homo sapiens | 3 | ALA5120844 | cell-based format | Scientific Literature | |
| 13. | ALA5123343 | F | Induction of osteoporosis in human MG-63 cells assessed as decrease in RANKL mRNA expression level at 10 uM by qRT-PCR analysis | Homo sapiens | 3 | ALA5120844 | cell-based format | Scientific Literature | |
| 14. | ALA5123344 | B | Inhibition of NF-kappaB transcriptional activity in human HeLa cells transfected with NF-kappaB-Luc by dual-luciferase reporter gene assay | Homo sapiens | 9 | ALA5120844 | cell-based format | Scientific Literature | |
| 15. | ALA5123346 | F | Anti-inflammatory activity against mouse RAW264.7 cells assessed as reduction in LPS-induced IL-1beta mRNA expression level preincubated for 1 hr followed by LPS addition and measured after 16 hrs by qRT-PCR analysis | Mus musculus | 4 | ALA5120844 | cell-based format | Scientific Literature | |
| 16. | ALA5123347 | F | Anti-inflammatory activity against mouse RAW264.7 cells assessed as reduction in LPS-induced IL-6 mRNA expression level preincubated for 1 hr followed by LPS addition and measured after 16 hrs by qRT-PCR analysis | Mus musculus | 3 | ALA5120844 | cell-based format | Scientific Literature | |
| 17. | ALA5123348 | F | Anti-inflammatory activity against mouse RAW264.7 cells assessed as reduction in LPS-induced COX-2 mRNA expression level preincubated for 1 hr followed by LPS addition and measured after 16 hrs by qRT-PCR analysis | Mus musculus | 3 | ALA5120844 | cell-based format | Scientific Literature | |
| 18. | ALA5123349 | F | Anti-inflammatory activity against mouse RAW264.7 cells assessed as reduction in LPS-induced GLIZ mRNA expression level preincubated for 1 hr followed by LPS addition and measured after 16 hrs by qRT-PCR analysis | Mus musculus | 4 | ALA5120844 | cell-based format | Scientific Literature |
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