# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5134501 | Functional | Induction of DNA damage in human T24 cells assessed as increase in gamma p53 expression at 0.5 to 1 uM incubated for 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA5131473 | cell-based format | Scientific Literature | |
2. | ALA5134502 | Functional | Induction of DNA damage in human T24 cells assessed as increase in gamma H2AX expression at 0.5 to 1 uM incubated for 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA5131473 | cell-based format | Scientific Literature | |
3. | ALA5134507 | Functional | Induction of DNA damage in human T24 cells assessed as DNA strand breakage by measuring comet formation at 0.5 uM incubated for 24 hrs by comet assay | Homo sapiens | 1 | ALA5131473 | cell-based format | Scientific Literature | |
4. | ALA5134509 | Toxicity | Cytotoxicity against human WI-38 cells by MTT assay | Homo sapiens | 3 | ALA5131473 | cell-based format | Scientific Literature | |
5. | ALA5134510 | Toxicity | Toxicity in BALB/C nude mouse xenografted with human T24 cells assessed as effect on liver at 30 mg/kg, IG administered every 2 days for 14 days by H and E staining based assay | Mus musculus | 3 | ALA5131473 | organism-based format | Scientific Literature | |
6. | ALA5134511 | Toxicity | Toxicity in BALB/C nude mouse xenografted with human T24 cells assessed as effect on lung at 30 mg/kg, IG administered every 2 days for 14 days by H and E staining based assay | Mus musculus | 3 | ALA5131473 | organism-based format | Scientific Literature | |
7. | ALA5134512 | Toxicity | Toxicity in BALB/C nude mouse xenografted with human T24 cells assessed as effect on kidney at 30 mg/kg, IG administered every 2 days for 14 days by H and E staining based assay | Mus musculus | 3 | ALA5131473 | organism-based format | Scientific Literature | |
8. | ALA5134513 | Functional | Antiproliferative activity against human HepG2 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay | Homo sapiens | 24 | ALA5131473 | cell-based format | Scientific Literature | |
9. | ALA5134514 | Functional | Antiproliferative activity against human MGC-803 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay | Homo sapiens | 24 | ALA5131473 | cell-based format | Scientific Literature | |
10. | ALA5134515 | Functional | Antiproliferative activity against human T24 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay | Homo sapiens | 24 | ALA5131473 | cell-based format | Scientific Literature | |
11. | ALA5134516 | Functional | Antiproliferative activity against human SK-OV-3 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay | Homo sapiens | 24 | ALA5131473 | cell-based format | Scientific Literature | |
12. | ALA5134517 | Functional | Antiproliferative activity against human WI-38 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay | Homo sapiens | 24 | ALA5131473 | cell-based format | Scientific Literature | |
13. | ALA5134518 | Toxicity | Cytotoxicity against human T24 cells assessed as decrease in cell viability measured after 48 hrs by MTT assay | Homo sapiens | 3 | ALA5131473 | cell-based format | Scientific Literature | |
14. | ALA5134522 | Functional | Inhibition of colony formation in human T24 cells at 0.01 uM incubated for 24 hrs and measured for 10 days | Homo sapiens | 1 | ALA5131473 | cell-based format | Scientific Literature | |
15. | ALA5134523 | Functional | Inhibition of cell migration in human T24 cells assessed as recovery of wound area at 0.25 uM measured after 24 hrs by wound healing assay based fluorescence microscopy | Homo sapiens | 1 | ALA5131473 | cell-based format | Scientific Literature | |
16. | ALA5134526 | Toxicity | Toxicity in human WI-38 cells assessed as wound closure at 0.25 uM measured after 24 hrs by fluorescence microscopy based wound healing assay | Homo sapiens | 1 | ALA5131473 | cell-based format | Scientific Literature | |
17. | ALA5134530 | Functional | Induction of cell cycle arrest in human T24 cells assessed as increase in Cyclin B expression at 0.5 to 1 uM incubated for 24 hrs by chemiluminescence based Western blotting analysis | Homo sapiens | 1 | ALA5131473 | cell-based format | Scientific Literature | |
18. | ALA5134531 | Functional | Induction of cell cycle arrest in human T24 cells assessed as increase in CDK1 expression at 0.5 to 1 uM incubated for 24 hrs by chemiluminescence based Western blotting analysis | Homo sapiens | 1 | ALA5131473 | cell-based format | Scientific Literature | |
19. | ALA5134536 | Functional | Induction of DNA damage in human T24 cells assessed as increase in gamma H2AX phosphorylation at 0.5 uM incubated for 24 hrs by Hoechst33258 staining based immunofluorescence assay | Homo sapiens | 1 | ALA5131473 | cell-based format | Scientific Literature | |
20. | ALA5134538 | Functional | Induction of apoptosis in human T24 cells assessed as condensation of nuclei at 0.5 uM by Hoechst33258 staining based fluorescence microscopy | Homo sapiens | 1 | ALA5131473 | cell-based format | Scientific Literature |