# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5099649 | B | Binding affinity to wild type TTR (unknown origin) assessed as dissociation constant by ITC assay | Homo sapiens | 6 | single protein format | Scientific Literature | ||
2. | ALA5099650 | B | Binding affinity to wild type TTR (unknown origin) assessed as gibbs free energy change by ITC analysis | Homo sapiens | 6 | single protein format | Scientific Literature | ||
3. | ALA5099651 | B | Anti-aggregation activity against wild type TTR (unknown origin) assessed as decrease in aggregation level measured after 30 mins followed by pH decrease and measured after 72 hrs by fluorescent based spectrophotometric analysis | Homo sapiens | 6 | single protein format | Scientific Literature | ||
4. | ALA5099652 | B | Binding affinity to wild type TTR (unknown origin) assessed as change in enthalpy by ITC analysis | Homo sapiens | 6 | single protein format | Scientific Literature | ||
5. | ALA5099653 | B | Binding affinity to wild type TTR (unknown origin) assessed as change in entropy by ITC analysis | Homo sapiens | 6 | single protein format | Scientific Literature | ||
6. | ALA5099656 | B | Anti-aggregation activity against wild type TTR (unknown origin) assessed as reduction in amyloid formation at 1:1 TTR to compound ratio measured after 30 mins followed by pH decrease and measured after 72 hrs by turbidity based analysis | Homo sapiens | 3 | single protein format | Scientific Literature |