# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5125087 | F | Anti-ferroptotic activity against RSL3-induced ferroptosis in human HT-22 cells assessed as cell viability measured after 24 hrs by MTT assay | Mus musculus | 7 | cell-based format | Scientific Literature | ||
2. | ALA5125089 | T | Cytotoxicity against human HT-22 cells assessed as reduction in cell viability measured after 24 hrs by MTT assay | Mus musculus | 10 | cell-based format | Scientific Literature | ||
3. | ALA5125090 | F | Reduction in lipid ROS accumulation in RSL-3 treated human HT-22 cells assessed as fluorescence intensity incubated for 4 hrs by C11-BODIPY staining based flow cytometry analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
4. | ALA5125091 | F | Reduction in cytosolic ROS accumulation in RSL-3 treated human HT-22 cells assessed as fluorescence intensity incubated for 4 hrs by carboxy-H2DCFDA staining based flow cytometry analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
5. | ALA5125092 | F | Reversal of RSL-3 induced PTGS2 mRNA expression in human HT-22 cells incubated for 4 hrs by qRT-PCT analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
6. | ALA5125093 | F | Inhibition of staurosporine-induced apoptosis in human HT-22 cells assessed as increase in cell viability at 2 uM measured after 24 hrs | Mus musculus | 1 | cell-based format | Scientific Literature | ||
7. | ALA5125094 | F | Inhibition of hydrogen peroxide-induced necrosis in human HT-22 cells assessed as increase in cell viability at 2 uM measured after 24 hrs | Mus musculus | 1 | cell-based format | Scientific Literature | ||
8. | ALA5125095 | F | Antioxidant activity assessed as DPPH radical scavenging activity at 100 uM measured for 30 mins by microplate spectrophotometric analysis | 7 | assay format | Scientific Literature | |||
9. | ALA5125096 | B | Metal chelating activity assessed as Fe2+-compound complex formation by UV-visible spectrophotometry | 2 | assay format | Scientific Literature |