# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5167410 | B | Positive allosteric modulator activity at human MRGPRX1 expressed in HEK293 cells assessed as maximal efficacy at 5 uM in presence of BAM8-22 by Fluo4-dye based FLIPR assay relative to control | Homo sapiens | 61 | cell-based format | Scientific Literature | ||
2. | ALA5167411 | B | Positive allosteric modulator activity at human MRGPRX1 expressed in HEK293 cells in presence of BAM8-22 by Fluo4-dye based FLIPR assay | Homo sapiens | 61 | cell-based format | Scientific Literature | ||
3. | ALA5167412 | A | Microsomal stability in human liver microsomes assessed as intrinsic clearance | Homo sapiens | 15 | microsome format | Scientific Literature | ||
4. | ALA5167413 | A | Microsomal stability in mouse liver microsomes assessed as intrinsic clearance | Mus musculus | 15 | microsome format | Scientific Literature | ||
5. | ALA5167414 | A | Plasma protein binding in human assessed as unbound fraction | Homo sapiens | 15 | cell-free format | Scientific Literature | ||
6. | ALA5167415 | A | Plasma protein binding in mouse assessed as unbound fraction | Homo sapiens | 15 | cell-free format | Scientific Literature |