# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5109012 | Binding | Protac activity at VHL/BCR-ABL in human K562 cells assessed as reduction in BCR-ABL protein levels incubated for 18 hrs by immunoblotting analysis | Homo sapiens | 1 | ALA5107965 | cell-based format | Scientific Literature | |
2. | ALA5109013 | Binding | Protac activity at VHL/BCR-ABL in human K562 cells assessed as reduction in BCR-ABL protein levels at 2.5 uM incubated for 18 hrs by immunoblotting analysis relative to control | Homo sapiens | 1 | ALA5107965 | cell-based format | Scientific Literature | |
3. | ALA5109014 | Functional | Antiproliferative activity against human K562 cells assessed as cell growth inhibition measured after 3 days by CellTiter glo assay | Homo sapiens | 1 | ALA5107965 | cell-based format | Scientific Literature | |
4. | ALA5109023 | Functional | Antiproliferative activity against mouse BaF3 cells harbouring BCR-ABL T315I mutant assessed as cell growth inhibition measured after 3 days by CellTiter glo assay | Mus musculus | 1 | ALA5107965 | cell-based format | Scientific Literature | |
5. | ALA5109024 | Functional | Antiproliferative activity against mouse BaF3 cells harbouring BCR-ABL G250E mutant assessed as cell growth inhibition measured after 3 days by CellTiter glo assay | Mus musculus | 1 | ALA5107965 | cell-based format | Scientific Literature |