# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5133627 | B | Displacement of [3H]-DTG from Sprague-Dawley rat liver Sigma 2 receptor incubated for 120 mins in presence of [3H]-(+)-pentazocine by liquid scintillation counting analysis | Rattus norvegicus | 15 | tissue-based format | Scientific Literature | ||
2. | ALA5133628 | B | Displacement of [3H]-(+)-pentazocine from Dunkin-Hartley guinea pig brain cortex Sigma 1 receptor incubated for 150 mins by liquid scintillation counting analysis | Cavia porcellus | 16 | tissue-based format | Scientific Literature | ||
3. | ALA5133629 | B | Displacement of [3H]-DAMGO from Sprague-Dawley rat brain membrane mu opioid receptor incubated for 45 mins by liquid scintillation counting analysis | Rattus norvegicus | 11 | cell membrane format | Scientific Literature | ||
4. | ALA5133630 | B | Displacement of [3H]-(2-D-Ala)[Tyrosy1-3,5-]-DELTORPHIN II from Sprague-Dawley rat brain membrane delta opioid receptor incubated for 45 mins by liquid scintillation counting analysis | Rattus norvegicus | 11 | cell membrane format | Scientific Literature | ||
5. | ALA5133631 | B | Displacement of [3H]-U69593 from Dunkin-Hartley guinea pig brain membrane kappa opioid receptor incubated for 30 mins by liquid scintillation counting analysis | Cavia porcellus | 11 | cell membrane format | Scientific Literature | ||
6. | ALA5133634 | F | Induction of H2S release in PBS buffer incubated for 1 hrs in presence of Washington State Probe-1 by spectrofluorimeter assay | 5 | assay format | Scientific Literature | |||
7. | ALA5133641 | T | Induction of motor coordination impairment in wild type CD1 mouse assessed as latency to fall at 40 mg/kg, sc measured upto 4 hrs by rotarod test | Mus musculus | 1 | organism-based format | Scientific Literature | ||
8. | ALA5133642 | T | Inhibition of human ERG potassium channel expressed in CHO-K1 cells at 1 uM by Qube-automated patch clamp assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
9. | ALA5133643 | T | Inhibition of human ERG potassium channel expressed in CHO-K1 cells at 10 uM by Qube-automated patch clamp assay relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
10. | ALA5133644 | T | Induction of hypotension in wild type CD1 mouse assessed as mean arterial blood pressure at 30 to 40 mg/kg, sc incubated upto 45 mins by tail-cuff plethysmography | Mus musculus | 1 | organism-based format | Scientific Literature | ||
11. | ALA5133645 | F | Analgesic activity in wild type CD1 mouse model of capsaicin-induced mechanical hypersensitivity assessed as reduction of capsaicin-induced mechanical hypersensitivity at 10 to 40 mg/kg, sc | Mus musculus | 4 | organism-based format | Scientific Literature | ||
12. | ALA5133646 | F | Analgesic activity in wild type CD1 mouse model of capsaicin-induced mechanical hypersensitivity assessed as reduction of capsaicin-induced mechanical hypersensitivity at 20 mg/kg, sc in presence of sigma1 receptor agonist PRE-084 | Mus musculus | 1 | organism-based format | Scientific Literature | ||
13. | ALA5133647 | F | Analgesic activity in wild type CD1 mouse model of capsaicin-induced mechanical hypersensitivity assessed as reduction of capsaicin-induced mechanical hypersensitivity at 40 mg/kg, sc in presence of sigma1 receptor agonist PRE-084 | Mus musculus | 3 | organism-based format | Scientific Literature | ||
14. | ALA5133648 | P | Stability of compound in phosphate buffer at pH 7.4 assessed as half life by UHPLC-PDA analysis | 1 | small-molecule physicochemical format | Scientific Literature | |||
15. | ALA5133649 | P | Stability of compound in saline solution assessed as half life by UHPLC-PDA analysis | 1 | small-molecule physicochemical format | Scientific Literature | |||
16. | ALA5133650 | P | Aqueous solubility of compound at 5 mg measured for 24 hrs by UHPLC-PDA analysis | 1 | small-molecule physicochemical format | Scientific Literature | |||
17. | ALA5133651 | T | Inhibition of human ERG potassium channel expressed in CHO-K1 cells by Qube-automated patch clamp assay | Homo sapiens | 1 | cell-based format | Scientific Literature |