| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5138117 | T | Selectivity index, ratio of CC50 for cytotoxicity against human Huh-5-2 cells carrying HCV subgenomic replicon assessed as decrease in intracellular ATP level to EC50 for antiviral activity against HCV GT-1b Con1 in human Huh-5-2 cells carrying HCV subgenomic replicon assessed as reduction of viral replication | 19 | ALA5136987 | cell-based format | Scientific Literature | ||
| 2. | ALA5138118 | F | Antiviral activity against HCV GT-1b Con1 in human Huh-5-2 cells carrying HCV subgenomic replicon assessed as reduction of viral replication measured after 72 hrs by Firefly luciferase reporter gene assay | Hepacivirus hominis | 21 | ALA5136987 | organism-based format | Scientific Literature | |
| 3. | ALA5138119 | T | Cytotoxicity against human Huh-5-2 cells carrying HCV subgenomic replicon assessed as decrease in intracellular ATP level measured after 72 hrs by Glo-max luminescence based assay | Homo sapiens | 21 | ALA5136987 | cell-based format | Scientific Literature | |
| 4. | ALA5138120 | F | Antiviral activity against HCV 3a S52 in human Huh7.5 cells carrying HCV subgenomic replicons assessed as inhibition of viral replication measured after 72 hrs by Firefly luciferase reporter gene assay | Hepacivirus hominis | 6 | ALA5136987 | organism-based format | Scientific Literature | |
| 5. | ALA5138122 | F | Antiviral activity against HCV 2a JFH1 in human Huh-7 cells carrying HCV subgenomic replicon assessed as inhibition of viral replication measured after 72 hrs by Firefly luciferase reporter gene assay | Hepatitis C virus | 6 | ALA5136987 | cell-based format | Scientific Literature | |
| 6. | ALA5138123 | F | Antiviral activity against HCV 4a ED43 in human Huh7.5 cells carrying HCV subgenomic replicon assessed as inhibition of viral replication measured after 72 hrs by Firefly luciferase reporter gene assay | Hepacivirus hominis | 6 | ALA5136987 | organism-based format | Scientific Literature | |
| 7. | ALA5138127 | A | Metabolic stability in human S9 fraction assessed as half life at 10 mg/ml measured upto 120 mins in presence of NADP degenerating system by LC-MS/MS analysis | Homo sapiens | 7 | ALA5136987 | subcellular format | Scientific Literature | |
| 8. | ALA5138128 | A | Metabolic stability in human S9 fraction assessed as clearance at 10 mg/ml measured upto 120 mins in presence of NADP degenerating system by LC-MS/MS analysis | Homo sapiens | 6 | ALA5136987 | subcellular format | Scientific Literature |
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