# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5112234 | B | Inhibition of recombinant human full length DNA polymerase theta using DNA substrate measured after 1 hrs in presence of dNTPs by plate reader assay | Homo sapiens | 41 | ALA5108060 | single protein format | Scientific Literature | |
2. | ALA5112236 | B | Displacement of tracer from recombinant Tb-labeled DNA polymerase theta (unknown origin) using DNA as substrate preincubated for 30 mins followed by compound addition for 2 hrs by HTRF assay | Homo sapiens | 4 | ALA5108060 | single protein format | Scientific Literature | |
3. | ALA5112237 | B | Displacement of tracer from recombinant Tb-labeled DNA polymerase theta (unknown origin) assessed as Kon using DNA as substrate preincubated for 30 mins followed by compound addition for 2 hrs by HTRF assay | Homo sapiens | 4 | ALA5108060 | single protein format | Scientific Literature | |
4. | ALA5112238 | B | Displacement of tracer from recombinant Tb-labeled DNA polymerase theta (unknown origin) assessed as Koff using DNA as substrate preincubated for 30 mins followed by compound addition for 2 hrs by HTRF assay | Homo sapiens | 4 | ALA5108060 | single protein format | Scientific Literature | |
5. | ALA5112239 | F | Inhibition of microhomology-mediated end joining in HEK293 cells | Homo sapiens | 13 | ALA5108060 | cell-based format | Scientific Literature | |
6. | ALA5112240 | F | Antiproliferative activity against human BRCA-2 deficient DLD-1 cells | Homo sapiens | 14 | ALA5108060 | cell-based format | Scientific Literature | |
7. | ALA5112241 | F | Antiproliferative activity against human DLD-1 cells | Homo sapiens | 14 | ALA5108060 | cell-based format | Scientific Literature | |
8. | ALA5112263 | B | Displacement of tracer from recombinant Tb-labeled DNA polymerase theta (unknown origin) assessed as end point Kd using DNA as substrate preincubated for 30 mins followed by compound addition for 2 hrs by HTRF assay | Homo sapiens | 10 | ALA5108060 | single protein format | Scientific Literature |