| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5097965 | B | Inhibition of recombinant HDAC3 (unknown origin) at 1 uM relative to control | Homo sapiens | 23 | single protein format | Scientific Literature | ||
| 2. | ALA5097966 | F | Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell viability measured for 48 hrs by microplate reader based MTT assay | Homo sapiens | 23 | cell-based format | Scientific Literature | ||
| 3. | ALA5097967 | F | Antiproliferative activity against mouse B16-F10 cells assessed as inhibition of cell viability measured for 48 hrs by microplate reader based MTT assay | Mus musculus | 23 | cell-based format | Scientific Literature | ||
| 4. | ALA5097968 | F | Antiproliferative activity against human Jurkat cells assessed as inhibition of cell viability measured for 48 hrs by microplate reader based CCK-8 assay | Homo sapiens | 23 | cell-based format | Scientific Literature | ||
| 5. | ALA5097969 | F | Antiproliferative activity against human A549 cells assessed as inhibition of cell viability measured for 48 hrs by microplate reader based CCK-8 assay | Homo sapiens | 23 | cell-based format | Scientific Literature | ||
| 6. | ALA5097977 | B | Inhibition of recombinant HDAC6 (unknown origin) at 1 uM relative to control | Homo sapiens | 9 | single protein format | Scientific Literature | ||
| 7. | ALA5097983 | B | Inhibition of full length recombinant human HDAC1 (1 to 482 residues) expressed in Baculovirus system using Ac-Leu-Gly-Lys (Ac)-AMC as substrate pretreated for 5 mins followed by substrate addition and measured after 30 mins | Homo sapiens | 23 | assay format | Scientific Literature | ||
| 8. | ALA5097984 | B | Inhibition of recombinant HDAC3 (unknown origin) using Ac-Leu-Gly-Lys (Ac)-AMC as substrate pretreated for 5 mins followed by substrate addition and measured after 30 mins | Homo sapiens | 23 | single protein format | Scientific Literature | ||
| 9. | ALA5097985 | B | Inhibition of full length N-terminal GST-tagged human recombinant HDAC6 (1 to 1215 residues) expressed in Baculovirus infected Sf9 cells using Ac-Leu-Gly-Lys (Ac)-AMC as substrate pretreated for 5 mins followed by substrate addition and measured after 30 mins | Homo sapiens | 23 | cell-based format | Scientific Literature | ||
| 10. | ALA5097986 | B | Inhibition of full length N-terminal GST-tagged human recombinant HDAC7 (501 to 952 residues) expressed in Baculovirus system using Ac-Leu-Gly-Lys (Ac)-AMC as substrate pretreated for 5 mins followed by substrate addition and measured after 30 mins | Homo sapiens | 23 | assay format | Scientific Literature | ||
| 11. | ALA5097987 | B | Inhibition of full length C-terminal his-tagged human recombinant HDAC8 (142 to 143 residues) expressed in baculovirus in Sf9 insect cells using Ac-Leu-Gly-Lys (Tfa)-AMC as substrate pretreated for 5 mins followed by substrate addition and measured after 30 mins | Homo sapiens | 23 | cell-based format | Scientific Literature | ||
| 12. | ALA5097990 | B | Selectivity index, ratio of IC50 for Inhibition of full length N-terminal GST-tagged human recombinant HDAC7 (501 to 952 residues) expressed in Baculovirus system using Ac-Leu-Gly-Lys (Ac)-AMC as substrate to IC50 for inhibition of full length N-terminal GST-tagged human recombinant HDAC6 (1 to 1215 residues) expressed in Baculovirus infected Sf9 cells using Ac-Leu-Gly-Lys (Ac)-AMC as substrate | Homo sapiens | 6 | cell-based format | Scientific Literature |
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