# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5111473 | F | Reversal of Ang II-induced proliferation in neonatal rat cardiac fibroblasts measured after 48 hrs by MTT assay | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
2. | ALA5111477 | B | Inhibition of KDM5B (unknown origin) at 10 uM incubated for 30 mins by HRTF assay relative to control | Homo sapiens | 39 | single protein format | Scientific Literature | ||
3. | ALA5111478 | B | Inhibition of KDM5B (unknown origin) incubated for 30 mins by HRTF assay | Homo sapiens | 33 | single protein format | Scientific Literature | ||
4. | ALA5111480 | B | Inhibition of KDM5A (unknown origin) incubated for 30 mins by HRTF assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
5. | ALA5111481 | B | Inhibition of KDM5C (unknown origin) incubated for 30 mins by HRTF assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
6. | ALA5111482 | T | Cytotoxicity against neonatal rat cardiac fibroblast assessed as cell survival rate at 10 uM measured after 48 hrs by MTT assay relative to control | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
7. | ALA5111483 | T | Cytotoxicity against neonatal rat Cardiomyocytes assessed as cell survival rate at 10 uM measured after 48 hrs by MTT assay | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
8. | ALA5111484 | B | Inhibition of KDM5B in neonatal rat cardiac fibroblasts assessed as increase in H3K4me3 protein level measured after 48 hrs by Western blot analysis | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
9. | ALA5111485 | F | Reversal of Ang II-induced increase in collagen I level in neonatal rat cardiac fibroblasts by Western blot analysis | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
10. | ALA5111486 | F | Reversal of Ang II-induced increase in collagen II level in neonatal rat cardiac fibroblasts by Western blot analysis | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
11. | ALA5111487 | F | Reversal of Ang II-induced increase in alpha-SMA level in neonatal rat cardiac fibroblasts by Western blot analysis | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
12. | ALA5111488 | F | Reversal of Ang II-induced decrease in H3K4me3 level in neonatal rat cardiac fibroblasts by Western blot analysis | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
13. | ALA5111489 | F | Reversal of Ang II-induced decrease in H3K4me3 level in neonatal rat cardiac fibroblasts by immunofluorescence staining assay | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
14. | ALA5111490 | F | Antimigratory activity in neonatal rat cardiac fibroblasts assessed as fold decrease in Ang II-induced migration measured after 48 hrs by scratch test | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
15. | ALA5111491 | F | Antimigratory activity in neonatal rat cardiac fibroblasts assessed as fold decrease in Ang II-induced migration measured after 48 hrs by transwell test (Rvb = 1.8 fold) | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
16. | ALA5111492 | A | Clearance in Sprague-Dawley rat at 2 mg/kg, iv measured upto 24 hrs | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
17. | ALA5111493 | A | Clearance in Sprague-Dawley rat at 10 mg/kg, po measured upto 24 hrs | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
18. | ALA5111494 | A | Volume of distribution at steady state in Sprague-Dawley rat at 10 mg/kg, po measured upto 24 hrs | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
19. | ALA5111495 | A | Volume of distribution at steady state in Sprague-Dawley rat at 2 mg/kg, iv measured upto 24 hrs | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
20. | ALA5111496 | A | Half life in Sprague-Dawley rat at 10 mg/kg, po measured upto 24 hrs | Rattus norvegicus | 1 | organism-based format | Scientific Literature |