# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5130697 | B | Inhibition of recombinant HDAC4 (unknown origin) using Boc-Lys(TFA)-AMC as substrate by fluorescence based plate reader assay | Homo sapiens | 10 | single protein format | Scientific Literature | ||
2. | ALA5130698 | B | Inhibition of recombinant HDAC5 (unknown origin) using Boc-Lys(TFA)-AMC as substrate by fluorescence based plate reader assay | Homo sapiens | 10 | single protein format | Scientific Literature | ||
3. | ALA5130699 | B | Inhibition of recombinant HDAC7 (unknown origin) using Boc-Lys(TFA)-AMC as substrate by fluorescence based plate reader assay | Homo sapiens | 10 | single protein format | Scientific Literature | ||
4. | ALA5130700 | B | Inhibition of recombinant HDAC9 (unknown origin) using Boc-Lys(TFA)-AMC as substrate by fluorescence based plate reader assay | Homo sapiens | 10 | single protein format | Scientific Literature | ||
5. | ALA5130701 | B | Inhibition of class 2a HDAC in human Jurkat E6.1 cells using Boc-Lys(TFA)-AMC as substrate incubated for 24 hrs by plate reader assay | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
6. | ALA5130702 | B | Inhibition of class 1 HDAC in human Jurkat E6.1 cells using Boc-Lys(Ac)-AMC as substrate incubated for 24 hrs by plate reader assay | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
7. | ALA5130703 | P | Kinetic aqueous solubility of the compound in PBS buffer at pH 7.4 incubated for 2 hrs under shaking condition by LC-UV analysis | 10 | small-molecule physicochemical format | Scientific Literature | |||
8. | ALA5130704 | B | Protac activity at VHL/HDAC4 in human Jurkat E6.1 cells assessed as induction of HDAC4 degradation incubated for 24 hrs by ELISA-based MSD electrochemiluminescence assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
9. | ALA5130705 | B | Protac activity at VHL/HDAC4 in human Jurkat E6.1 cells assessed as induction of HDAC4 degradation by measuring maximum degradation at 10 uM incubated for 24 hrs by ELISA-based MSD electrochemiluminescence assay relative to control | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
10. | ALA5130706 | B | Protac activity at VHL/HDAC4 in human Jurkat E6.1 cells assessed as induction of HDAC4 degradation at 10 uM incubated for 24 hrs by immunoblotting analysis | Homo sapiens | 2 | cell-based format | Scientific Literature |