| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5145397 | A | Clearance in human liver microsomes at 1 uM in presence of NADPH measured for 15 to 30 min by LC-MS/MS analysis | Homo sapiens | 8 | ALA5143566 | microsome format | Scientific Literature | |
| 2. | ALA5145401 | B | Positive allosteric modulator activity at GluN1a/GluN2A (unknown origin) expressed in CHO cells in presence of glutamate by Ca2+ influx assay | Homo sapiens | 13 | ALA5143566 | cell-based format | Scientific Literature | |
| 3. | ALA5145402 | B | Positive allosteric modulator activity at GluN1a/GluN2A (unknown origin) expressed in CHO cells assessed as maximum potentiation at 30 uM in presence of glutamate by Ca2+ influx assay relative to control | Homo sapiens | 16 | ALA5143566 | cell-based format | Scientific Literature | |
| 4. | ALA5145403 | P | 1-Octanol/aqueous buffer distribution coefficient, log D of the compound at pH 7.4 by HPLC analysis | 17 | ALA5143566 | small-molecule physicochemical format | Scientific Literature | ||
| 5. | ALA5145404 | B | Displacement of [3H]-HBT1 from His-tagged GluA2-AMPA (unknown origin) receptor expressed in CHO cells in presence of glutamate by scintillation proximity assay | Homo sapiens | 16 | ALA5143566 | cell-based format | Scientific Literature | |
| 6. | ALA5145405 | A | Clearance in rat liver microsomes at 1 uM in presence of NADPH measured for 15 to 30 min by LC-MS/MS analysis | Rattus norvegicus | 8 | ALA5143566 | microsome format | Scientific Literature |
The page will load shortly, Thanks for your patience!