# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5140111 | Binding | Inhibition of human N-terminal SUMO-tagged DHODH expressed in Escherichia coli BL21(DE3) at 1 uM using dihydroorotate as substrate by DCIP based microplate reader analysis relative to control | Homo sapiens | 39 | ALA5137035 | assay format | Scientific Literature | |
2. | ALA5140112 | Binding | Inhibition of human N-terminal SUMO-tagged DHODH expressed in Escherichia coli BL21(DE3) at 100 nM using dihydroorotate as substrate by DCIP based microplate reader analysis relative to control | Homo sapiens | 39 | ALA5137035 | assay format | Scientific Literature | |
3. | ALA5140113 | Binding | Inhibition of human N-terminal SUMO-tagged DHODH expressed in Escherichia coli BL21(DE3) using dihydroorotate substrate by DCIP based microplate reader analysis | Homo sapiens | 32 | ALA5137035 | assay format | Scientific Literature | |
4. | ALA5140114 | Functional | Antiproliferative activity against human Raji cells assessed as cell growth inhibition measured after 96 hrs by MTT assay | Homo sapiens | 8 | ALA5137035 | cell-based format | Scientific Literature | |
5. | ALA5140115 | Functional | Antiproliferative activity against human A375 cells expressing human DHODH assessed as reduction in cell viability measured after 96 hrs by MTT assay | Homo sapiens | 2 | ALA5137035 | cell-based format | Scientific Literature | |
6. | ALA5140116 | Functional | Antiproliferative activity against human HCT-116 cells expressing human DHODH assessed as reduction in cell viability measured after 96 hrs by MTT assay | Homo sapiens | 3 | ALA5137035 | cell-based format | Scientific Literature | |
7. | ALA5140117 | Functional | Antiproliferative activity against human Kasumi 1 cells expressing human DHODH assessed as reduction in cell viability measured after 96 hrs by MTT assay | Homo sapiens | 2 | ALA5137035 | cell-based format | Scientific Literature | |
8. | ALA5140118 | Functional | Antiproliferative activity against human KG-1 cells expressing human DHODH assessed as reduction in cell viability measured after 96 hrs by MTT assay | Homo sapiens | 2 | ALA5137035 | cell-based format | Scientific Literature | |
9. | ALA5140119 | Functional | Antiproliferative activity against human U-937 cells expressing human DHODH assessed as reduction in cell viability measured after 96 hrs by MTT assay | Homo sapiens | 2 | ALA5137035 | cell-based format | Scientific Literature | |
10. | ALA5140120 | Functional | Antiproliferative activity against human SU-DHL-4 cells expressing human DHODH assessed as reduction in cell viability measured after 96 hrs by MTT assay | Homo sapiens | 2 | ALA5137035 | cell-based format | Scientific Literature | |
11. | ALA5140121 | Toxicity | Cytotoxicity against human HL7702 cells expressing human DHODH assessed as reduction in cell viability measured after 96 hrs by MTT assay | Homo sapiens | 2 | ALA5137035 | cell-based format | Scientific Literature | |
12. | ALA5140122 | Toxicity | Cytotoxicity against human HCoEpiC cells expressing human DHODH assessed as reduction in cell viability measured after 96 hrs by MTT assay | Homo sapiens | 2 | ALA5137035 | cell-based format | Scientific Literature | |
13. | ALA5140123 | Toxicity | Acute toxicity in BALB/c mouse assessed as decrease in body weight at 300 mg/kg, po measured for 14 days | Mus musculus | 1 | ALA5137035 | organism-based format | Scientific Literature | |
14. | ALA5140124 | Toxicity | Toxicity in BALB/c mouse assessed as animal death at 300 mg/kg, po measured for 14 days | Mus musculus | 1 | ALA5137035 | organism-based format | Scientific Literature |