# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5144282 | F | Antiviral activity against Influenza A virus A/WSN/33(H1N1) infected in MDCK cells assessed as reduction in virus induced cytopathic effect measured 48 hrs post infection by MTT assay | Influenza A virus | 32 | ALA5143520 | organism-based format | Scientific Literature | |
2. | ALA5144283 | T | Cytotoxicity against MDCK cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay | Canis lupus familiaris | 32 | ALA5143520 | cell-based format | Scientific Literature | |
3. | ALA5144284 | T | Selectivity index, ratio of CC50 for cytotoxicity against MDCK cells to EC50 for antiviral activity against Influenza A virus A/WSN/33(H1N1) infected in MDCK cells | 32 | ALA5143520 | cell-based format | Scientific Literature | ||
4. | ALA5144285 | F | Antiviral activity against Influenza A virus A/WSN/33(H1N1) infected in human A549 cells assessed as reduction in nucleoprotein expression at 5 to 20 uM measured 24 hrs post infection by Western blot analysis | Influenza A virus | 1 | ALA5143520 | organism-based format | Scientific Literature | |
5. | ALA5144286 | F | Antiviral activity against Influenza A virus A/WSN/33(H1N1) infected in human A549 cells assessed as reduction in nucleoprotein mRNA expression at 5 to 20 uM measured 24 hrs post infection by qRT-PCR analysis | Influenza A virus | 1 | ALA5143520 | organism-based format | Scientific Literature | |
6. | ALA5144287 | F | Antiviral activity against Influenza A virus A/WSN/33(H1N1) infected in MDCK cells assessed as reduction in nucleoprotein mRNA expression at 20 uM measured after 0 to 10 hrs by Western blot based time-of-addition assay | Influenza A virus | 1 | ALA5143520 | organism-based format | Scientific Literature | |
7. | ALA5144288 | F | Antiviral activity against Influenza A virus A/WSN/33(H1N1) infected in MDCK cells assessed as inhibition of virus replication and translation by measuring reduction in nucleoprotein mRNA expression at 20 uM measured after 2 to 8 hrs by Western blot based time-of-addition assay | Influenza A virus | 1 | ALA5143520 | organism-based format | Scientific Literature | |
8. | ALA5144289 | F | Antiviral activity against Influenza A virus A/WSN/33(H1N1) infected in MDCK cells assessed as distribution of PAN protein expression in nucleus and cytoplasm measured 24 hrs post infection by DAPI staining based microscopic analysis | Influenza A virus | 1 | ALA5143520 | organism-based format | Scientific Literature | |
9. | ALA5144290 | B | Inhibition of Influenza A virus N-terminal domain of PA endonuclease using 6FAM-TGGCAATATCAGCTCCACA-MGBNFQ as fluorescent substrate by FRET analysis | Influenza A virus | 9 | ALA5143520 | single protein format | Scientific Literature |