| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5120154 | B | Inhibition of human recombinant AChe using acetylthiocholine iodide as substrate incubated for 10 mins by DTNB reagent based Ellman's method | Homo sapiens | 25 | single protein format | Scientific Literature | ||
| 2. | ALA5120155 | B | Inhibition of human recombinant BuChe using butyrylthiocholine iodide as substrate incubated for 10 mins by DTNB reagent based Ellman's method | Homo sapiens | 25 | single protein format | Scientific Literature | ||
| 3. | ALA5120156 | B | Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane measured after 120 mins by scintillation counting method | Cavia porcellus | 26 | cell membrane format | Scientific Literature | ||
| 4. | ALA5120157 | B | Displacement of [3H]DTG from sigma 2 receptor in rat liver membranes measured after 120 mins by scintillation counting method | Rattus norvegicus | 25 | cell membrane format | Scientific Literature | ||
| 5. | ALA5120158 | B | Selectivity index, ratio of Ki for displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane to Ki for displacement of [3H]DTG from sigma 2 receptor in rat liver membranes | 7 | cell membrane format | Scientific Literature | |||
| 6. | ALA5120160 | B | Displacement of [3H]ifenprodil from recombinant human GluN2B NMDA receptor (unknown origin) expressed in dexamethasone-induced mouse L-M(TK-) cell after 120 mins by microbeta scintillation counting method | Homo sapiens | 23 | cell-based format | Scientific Literature | ||
| 7. | ALA5120161 | B | Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as reduction in YO-PRO-1 iodide dye uptake preincubated for 30 mins followed by YO-PRO-1 iodide addition and measured after 120 mins by fluorescence plate reader analysis | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
| 8. | ALA5120164 | F | Neuroprotective activity in H2O2 induced stress human SH-SY5Y cell model measured after 48 hrs by MTT assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 9. | ALA5120165 | F | Neuroprotective activity in Abeta42 induced stress human SH-SY5Y cell model measured after 72 hrs by CTG luminescence assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 10. | ALA5120170 | F | Neuroprotective activity against Abeta42 induced zebrafish AD model assessed as reversal of reduction in synaptic integrity at 10 uM measured after 5 days | Danio rerio | 8 | organism-based format | Scientific Literature | ||
| 11. | ALA5120177 | A | Inhibition of CYP3A4 (unknown origin) preincubated for 10 mins followed by NADP addition measured after 50 mins | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 12. | ALA5120178 | A | Inhibition of CYP2C9 (unknown origin) preincubated for 10 mins followed by NADP addition measured after 50 mins | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 13. | ALA5120179 | A | Inhibition of CYP2D6 (unknown origin) preincubated for 10 mins followed by NADP addition measured after 50 mins | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 14. | ALA5120180 | F | Anti-neuroinflammatory activity in Abeta42 induced zebrafish AD model assessed as reduction in number of activated microglia relative to control | Danio rerio | 3 | organism-based format | Scientific Literature |
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