# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5160701 | Functional | Antiproliferative activity against human A549 cells highly expressing EGFR after 48 hrs by MTT assay | Homo sapiens | 21 | ALA5154779 | cell-based format | Scientific Literature | |
2. | ALA5160702 | Functional | Cytotoxicity against human K562 cells after 48 hrs by MTT assay | Homo sapiens | 23 | ALA5154779 | cell-based format | Scientific Literature | |
3. | ALA5160703 | Functional | Cytotoxicity against human K562/A02 cells after 48 hrs by MTT assay | Homo sapiens | 23 | ALA5154779 | cell-based format | Scientific Literature | |
4. | ALA5160704 | Functional | Cytotoxicity against dog MDCK cells after 48 hrs by MTT assay | Canis lupus familiaris | 22 | ALA5154779 | cell-based format | Scientific Literature | |
5. | ALA5160705 | Functional | Cytotoxicity against dog MDCK-II-BCRP cells after 48 hrs by MTT assay | Canis lupus familiaris | 22 | ALA5154779 | cell-based format | Scientific Literature | |
6. | ALA5160706 | Binding | Reversal of P-gp-mediated multidrug resistance in human K562/A02 cells assessed as potentiation of adriamycin-induced cytotoxicity at 5 uM by measuring adriamycin IC50 after 48 hrs by MTT assay | Homo sapiens | 24 | ALA5154779 | cell-based format | Scientific Literature | |
7. | ALA5160707 | Binding | Reversal of BCRP-mediated multidrug resistance in dog MDCK-II-BCRP cells assessed as potentiation of mitoxantrone-induced cytotoxicity at 5 uM by measuring mitoxantrone IC50 after 48 hrs by MTT assay | Canis lupus familiaris | 24 | ALA5154779 | cell-based format | Scientific Literature | |
8. | ALA5160708 | Binding | Reversal of P-gp-mediated multidrug resistance in human K562/A02 cells assessed as fold reduction in adriamycin IC50 at 5 uM measured after 48 hrs by MTT assay relative to adriamycin IC50 alone | Homo sapiens | 24 | ALA5154779 | cell-based format | Scientific Literature | |
9. | ALA5160709 | Binding | Reversal of BCRP-mediated multidrug resistance in dog MDCK-II-BCRP cells assessed as fold reduction in mitoxantrone IC50 at 5 uM measured after 48 hrs by MTT assay relative to mitoxantrone IC50 alone | Canis lupus familiaris | 24 | ALA5154779 | cell-based format | Scientific Literature |