| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5146685 | B | Inhibition of human recombinant cRAF measured after 1 hr by TR-FRET assay | Homo sapiens | 20 | single protein format | Scientific Literature | ||
| 2. | ALA5146686 | F | Growth inhibition of human H358 cells expressing KRAS G21C mutant measured after 3 days by Cell-titer Glo assay | Homo sapiens | 20 | cell-based format | Scientific Literature | ||
| 3. | ALA5146687 | F | Effect on Erk signalling pathway in human H358 cells assessed as increase in Erk phosphorylation by HTRF assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 4. | ALA5146692 | A | Inhibition of CYP1A2 in human liver microsomes | Homo sapiens | 2 | microsome format | Scientific Literature | ||
| 5. | ALA5146693 | A | Inhibition of CYP2C9 in human liver microsomes | Homo sapiens | 2 | microsome format | Scientific Literature | ||
| 6. | ALA5146694 | A | Inhibition of CYP2C19 in human liver microsomes | Homo sapiens | 2 | microsome format | Scientific Literature | ||
| 7. | ALA5146695 | B | Inhibition of CYP2D6 in human liver microsomes | Homo sapiens | 2 | microsome format | Scientific Literature | ||
| 8. | ALA5146696 | B | Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate | Homo sapiens | 2 | microsome format | Scientific Literature | ||
| 9. | ALA5146697 | B | Inhibition of CYP3A4 in human liver microsomes using testosterone as substrate | Homo sapiens | 2 | microsome format | Scientific Literature | ||
| 10. | ALA5146698 | A | Stability of compound in human liver microsomes assessed as half life | Homo sapiens | 2 | microsome format | Scientific Literature | ||
| 11. | ALA5146699 | A | Stability of compound in mouse liver microsomes assessed as half life | Mus musculus | 2 | microsome format | Scientific Literature | ||
| 12. | ALA5146700 | A | Stability of compound in rat liver microsomes assessed as half life | Rattus norvegicus | 2 | microsome format | Scientific Literature | ||
| 13. | ALA5146701 | A | Stability of compound in Dog liver microsomes assessed as half life | Canis lupus familiaris | 2 | microsome format | Scientific Literature | ||
| 14. | ALA5146702 | A | Hepatic clearance in human liver microsomes | Homo sapiens | 2 | microsome format | Scientific Literature | ||
| 15. | ALA5146703 | A | Hepatic clearance in mouse liver microsomes | Mus musculus | 2 | microsome format | Scientific Literature | ||
| 16. | ALA5146704 | A | Hepatic clearance in rat liver microsomes | Rattus norvegicus | 2 | microsome format | Scientific Literature | ||
| 17. | ALA5146705 | A | Hepatic clearance in dog liver microsomes | Canis lupus familiaris | 2 | microsome format | Scientific Literature | ||
| 18. | ALA5146706 | P | Solubility of compound in PBS at pH 7.4 | 2 | small-molecule physicochemical format | Scientific Literature | |||
| 19. | ALA5146707 | T | Inhibition of hERG | Homo sapiens | 2 | assay format | Scientific Literature |
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