# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5116076 | B | Binding affinity to N-terminal MRGS(His)6GSDDDDK-tagged Matriptase (unknown origin) expressed in Escherichia coli assessed as inhibition constant using Mes-DArg-Pro-Arg-AMC as substrate | Homo sapiens | 23 | assay format | Scientific Literature | ||
2. | ALA5116077 | B | Binding affinity to bovine thrombin assessed as inhibition constant using tosyl-Gly-Pro-Arg-AMC as substrate | Bos taurus | 23 | single protein format | Scientific Literature | ||
3. | ALA5116078 | B | Binding affinity to FXa (unknown origin) using Mes-DArg-Pro-Arg-AMC as substrate | Homo sapiens | 23 | single protein format | Scientific Literature | ||
4. | ALA5116079 | B | Selectivity ratio of Ki for binding affinity to bovine thrombin assessed as inhibition constant using tosyl-Gly-Pro-Arg-AMC as substrate to Ki for binding affinity to N-terminal MRGS(His)6GSDDDDK-tagged Matriptase (unknown origin) expressed in Escherichia coli assessed as inhibition constant using Mes-DArg-Pro-Arg-AMC as substrate | Homo sapiens | 23 | assay format | Scientific Literature | ||
5. | ALA5116080 | B | Selectivity ratio of Ki for binding affinity to FXa (unknown origin) using Mes-DArg-Pro-Arg-AMC as substrate to Ki for binding affinity to N-terminal MRGS(His)6GSDDDDK-tagged Matriptase (unknown origin ) expressed in Escherichia coli assessed as inhibition constant using Mes-DArg-Pro-Arg-AMC as substrate | Homo sapiens | 23 | assay format | Scientific Literature | ||
6. | ALA5116081 | B | Binding affinity to bovine trypsin assessed as inhibition constant by hanging drop vapor diffusion analysis | Bos taurus | 2 | assay format | Scientific Literature | ||
7. | ALA5116082 | T | Cytotoxicity against MDCK-II cells assessed as reduction in cell viability at 50 uM measured for 24 hrs by Celltiter-glo luminescent assay | Canis lupus familiaris | 4 | cell-based format | Scientific Literature | ||
8. | ALA5116083 | F | Antiviral activity against Influenza A virus H9N2 infected in MDCK-II cells assessed as inhibition of viral replication measured after 24 hrs by immunostaining based assay | Influenza A virus | 4 | organism-based format | Scientific Literature | ||
9. | ALA5116084 | F | Antiviral activity against Influenza A virus H9N2 infected in MDCK-II cells assessed as reduction in comet-shaped foci at 50 uM measured after 24 hrs by immunostaining based assay | Influenza A virus | 4 | organism-based format | Scientific Literature | ||
10. | ALA5116085 | F | Antiviral activity against Influenza A virus H9N2 infected in MDCK-II cells assessed as reduction in comet-shaped foci at 20 uM measured after 24 hrs by immunostaining based assay | Influenza A virus | 4 | organism-based format | Scientific Literature | ||
11. | ALA5116086 | F | Antiviral activity against Influenza A virus H9N2 infected in MDCK-II cells assessed as reduction in viral titer in supernatants at 5 to 50 uM measured after 24 hrs by plaque assay | Influenza A virus | 4 | organism-based format | Scientific Literature |