| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5144846 | B | Inhibition of wild-type Transthyretin (unknown origin) expressed in Escherichia coli expression system assessed as acid mediated fibril formation at 7.2 uM measured after 72 hrs by UV-vis spectrophotometry | Homo sapiens | 10 | assay format | Scientific Literature | ||
| 2. | ALA5144847 | B | Inhibition of wild-type Transthyretin (unknown origin) expressed in Escherichia coli expression system assessed as acid mediated fibril formation at 3.6 uM measured after 72 hrs by UV-vis spectrophotometry | Homo sapiens | 9 | assay format | Scientific Literature | ||
| 3. | ALA5144848 | B | Inhibition of Transthyretin V30M mutant (unknown origin) assessed as acid mediated fibril formation at 3.6 uM measured after 72 hrs by UV-vis spectrophotometry | Homo sapiens | 5 | single protein format | Scientific Literature | ||
| 4. | ALA5144849 | B | Inhibition of Transthyretin V30M mutant (unknown origin) assessed as acid mediated fibril formation at 1.8 uM measured after 72 hrs by UV-vis spectrophotometry | Homo sapiens | 5 | single protein format | Scientific Literature | ||
| 5. | ALA5144851 | B | Inhibition of urea-induced Transthyretin denaturation in human plasma preincubated for 1 hr followed by urea addition by Western blot analysis | Homo sapiens | 5 | cell-free format | Scientific Literature |
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