| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5139311 | B | Inhibition of CDK9/Cyclin T1 (unknown origin) preincubated for 10 mins followed by ATP and CTD3 addition and measured after 30 mins by mobility shift assay | Homo sapiens | 28 | protein complex format | Scientific Literature | ||
| 2. | ALA5139312 | F | Antiproliferative activity against human MV4-11 cells assessed as inhibition of cell growth incubated for 72 hrs by CTG- luminescence assay | Homo sapiens | 21 | cell-based format | Scientific Literature | ||
| 3. | ALA5139314 | P | Kinetic solubility of the compound in pH 7.4 PBS buffer incubated for 24 hrs under shaking condition by HPLC analysis | 3 | small-molecule physicochemical format | Scientific Literature | |||
| 4. | ALA5139315 | A | Initial plasma concentration in Sprague-Dawley rat at 1 mg/kg, iv bolus injection measured upto 24 hrs by LC-MS/MS analysis | Rattus norvegicus | 3 | organism-based format | Scientific Literature | ||
| 5. | ALA5139316 | A | Elimination rate constant in Sprague-Dawley rat at 1 mg/kg, iv bolus injection measured upto 24 hrs by LC-MS/MS analysis | Rattus norvegicus | 3 | organism-based format | Scientific Literature | ||
| 6. | ALA5139317 | A | Half life in Sprague-Dawley rat at 1 mg/kg, iv bolus injection measured upto 24 hrs by LC-MS/MS analysis | Rattus norvegicus | 3 | organism-based format | Scientific Literature | ||
| 7. | ALA5139318 | A | MRT(0 to t) in Sprague-Dawley rat at 1 mg/kg, iv bolus injection measured upto 24 hrs by LC-MS/MS analysis | Rattus norvegicus | 3 | organism-based format | Scientific Literature | ||
| 8. | ALA5139319 | A | MRT(0 to infinity) in Sprague-Dawley rat at 1 mg/kg, iv bolus injection measured upto 24 hrs by LC-MS/MS analysis | Rattus norvegicus | 3 | organism-based format | Scientific Literature | ||
| 9. | ALA5139320 | A | AUC(0 to t) in Sprague-Dawley rat at 1 mg/kg, iv bolus injection measured upto 24 hrs by LC-MS/MS analysis | Rattus norvegicus | 3 | organism-based format | Scientific Literature | ||
| 10. | ALA5139321 | A | AUC(0 to infinity) in Sprague-Dawley rat at 1 mg/kg, iv bolus injection measured upto 24 hrs by LC-MS/MS analysis | Rattus norvegicus | 3 | organism-based format | Scientific Literature | ||
| 11. | ALA5139322 | A | Clearance in Sprague-Dawley rat at 1 mg/kg, iv bolus injection measured upto 24 hrs by LC-MS/MS analysis | Rattus norvegicus | 3 | organism-based format | Scientific Literature | ||
| 12. | ALA5139323 | A | Volume of distribution at steady state in Sprague-Dawley rat at 1 mg/kg, iv bolus injection measured upto 24 hrs by LC-MS/MS analysis | Rattus norvegicus | 3 | organism-based format | Scientific Literature | ||
| 13. | ALA5139324 | B | Inhibition of CDK1/cyclin B1 (unknown origin) preincubated for 10 mins followed by ATP and substrate addition and measured after 60 mins by HTRF analysis | Homo sapiens | 1 | protein complex format | Scientific Literature | ||
| 14. | ALA5139325 | B | Inhibition of CDK2/cyclin A2 (unknown origin) preincubated for 10 mins followed by ATP and substrate addition and measured after 60 mins by HTRF analysis | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 15. | ALA5139326 | B | Inhibition of CDK4/cyclin D3 (unknown origin) preincubated for 10 mins followed by ATP and substrate addition and measured after 60 mins by HTRF analysis | Homo sapiens | 1 | protein complex format | Scientific Literature | ||
| 16. | ALA5139327 | B | Inhibition of CDK6/cyclin D3 (unknown origin) preincubated for 10 mins followed by ATP and substrate addition and measured after 60 mins by HTRF analysis | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 17. | ALA5139328 | B | Inhibition of CDK7/cyclin H (unknown origin) preincubated for 10 mins followed by ATP and substrate addition and measured after 60 mins by HTRF analysis | Homo sapiens | 1 | protein complex format | Scientific Literature | ||
| 18. | ALA5139329 | B | Inhibition of CDK8/cyclin C (unknown origin) preincubated for 10 mins followed by ATP and substrate addition and measured after 60 mins by HTRF analysis | Homo sapiens | 1 | protein complex format | Scientific Literature | ||
| 19. | ALA5139330 | B | Inhibition of CDK12/cyclin K (unknown origin) preincubated for 10 mins followed by ATP and substrate addition and measured after 60 mins by HTRF analysis | Homo sapiens | 1 | protein complex format | Scientific Literature | ||
| 20. | ALA5139331 | B | Selectivity index, ratio of IC50 for inhibition of CDK2/cyclin A2 (unknown origin) to IC50 for inhibition of CDK9/Cyclin T1 (unknown origin) | Homo sapiens | 1 | assay format | Scientific Literature |
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