# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5112649 | B | Binding affinity to 15N-labeled recombinant human PBRM1 BD2 transfected in Escherichia coli BL21 (DE3) assessed as thermal stabilization by measuring change in melting temperature at 100 uM by SYPRO orange dye based differential scanning fluorimetry analysis | Homo sapiens | 40 | assay format | Scientific Literature | ||
2. | ALA5112650 | B | Inhibition of biotinylated histone H3K14 (1 to 20 residues) peptide binding to His6-tagged recombinant human PBRM1 BD2 transfected in Escherichia coli BL21 (DE3) incubated for 30 mins by Alphascreen assay | Homo sapiens | 32 | assay format | Scientific Literature | ||
3. | ALA5112657 | B | Binding affinity to His-TEV-tagged human PBRM1 BD5 transfected in Escherichia coli BL21 (DE3) assessed as thermal stabilization by measuring change in melting temperature at 100 uM by SYPRO orange dye based differential scanning fluorimetry analysis | Homo sapiens | 6 | assay format | Scientific Literature | ||
4. | ALA5112662 | B | Binding affinity to His-TEV-tagged human PBRM1 BD3 transfected in Escherichia coli BL21 (DE3) assessed as thermal stabilization by measuring change in melting temperature at 100 uM by SYPRO orange dye based differential scanning fluorimetry analysis | Homo sapiens | 3 | assay format | Scientific Literature | ||
5. | ALA5112665 | T | Cytotoxicity against HEK293T cells assessed as inhibition of cell growth at >=10 uM measured after 5 days by celltiter-glo assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
6. | ALA5112667 | T | Cytotoxicity against human RWPE-1 cells assessed as inhibition of cell growth at >=10 uM measured after 7 days with compound replacement for every 48 hrs by celltiter-glo assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
7. | ALA5112669 | F | Cytotoxicity against human PC-3 cells assessed as inhibition of cell growth measured after 6 days with compound replacement for every 48 hrs by celltiter-glo assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
8. | ALA5112672 | F | Cytotoxicity against human LNCaP cells assessed as inhibition of cell growth measured after 7 days with compound replacement for every 48 hrs by celltiter-glo assay | Homo sapiens | 4 | cell-based format | Scientific Literature |