# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5120624 | B | Inhibition of JAK1/JAK3 in human primary T-cells assessed as reduction of IL-2 stimulated STAT5 phosphorylation preincubated for 1 hr followed by IL-2 stimulation for 15 mins by FACS method | Homo sapiens | 33 | cell-based format | Scientific Literature | ||
2. | ALA5120628 | F | Inhibition of IL-2 stimulated IFN-gamma production in BALB/c mouse at 40 mg/kg, po pretreated for 30 mins followed by IL-2 stimulation and measured after 4 hrs by ELISA | Mus musculus | 15 | organism-based format | Scientific Literature | ||
3. | ALA5120649 | A | Oral bioavailability in Sprague-Dawley rat 5 mg/kg | Rattus norvegicus | 6 | organism-based format | Scientific Literature |