# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5135838 | F | Agonist activity at human 5HT2A receptor stably expressed in Flp-In-T-REx-293 cells assessed as increase in Gq-mediated calcium flux by Fluo-4 direct dye based FLIPR Tetra assay | Homo sapiens | 104 | ALA5131517 | cell-based format | Scientific Literature | |
2. | ALA5135839 | F | Agonist activity at human 5HT2A receptor stably expressed in Flp-In-T-REx-293 cells assessed as maximal Gq-mediated calcium flux by Fluo-4 direct dye based FLIPR Tetra assay relative to control | Homo sapiens | 98 | ALA5131517 | cell-based format | Scientific Literature | |
3. | ALA5135840 | F | Agonist activity at human 5HT2C receptor stably expressed in Flp-In-T-REx-293 cells assessed as increase in Gq-mediated calcium flux by Fluo-4 direct dye based FLIPR Tetra assay | Homo sapiens | 104 | ALA5131517 | cell-based format | Scientific Literature | |
4. | ALA5135841 | F | Agonist activity at human 5HT2C receptor stably expressed in Flp-In-T-REx-293 cells assessed as maximal Gq-mediated calcium flux by Fluo-4 direct dye based FLIPR Tetra assay relative to control | Homo sapiens | 94 | ALA5131517 | cell-based format | Scientific Literature | |
5. | ALA5135842 | B | Selectivity index, log ratio of Emax for agonist activity at human 5HT2C receptor expressed in Flp-In-T-REx-293 cells to EC50 for agonist activity at human 5HT2A receptor expressed in Flp-In-T-REx-293 cells | Homo sapiens | 90 | ALA5131517 | cell-based format | Scientific Literature | |
6. | ALA5135843 | F | Agonist activity at human 5HT2B receptor stably expressed in Flp-In-T-REx-293 cells assessed as increase in Gq-mediated calcium flux by Fluo-4 direct dye based FLIPR Tetra assay | Homo sapiens | 26 | ALA5131517 | cell-based format | Scientific Literature | |
7. | ALA5135844 | F | Agonist activity at human 5HT2B receptor stably expressed in Flp-In-T-REx-293 cells assessed as maximal Gq-mediated calcium flux by Fluo-4 direct dye based FLIPR Tetra assay relative to control | Homo sapiens | 24 | ALA5131517 | cell-based format | Scientific Literature | |
8. | ALA5135845 | B | Binding affinity to 5HT2C receptor (unknown origin) assessed as inhibition constant | Homo sapiens | 4 | ALA5131517 | single protein format | Scientific Literature | |
9. | ALA5135846 | B | Binding affinity to 5HT3 receptor (unknown origin) assessed as inhibition constant | Homo sapiens | 2 | ALA5131517 | single protein format | Scientific Literature | |
10. | ALA5135848 | B | Binding affinity to 5HT5A receptor (unknown origin) assessed as inhibition constant | Homo sapiens | 4 | ALA5131517 | single protein format | Scientific Literature | |
11. | ALA5135849 | B | Binding affinity to 5HT6 receptor (unknown origin) assessed as inhibition constant | Homo sapiens | 4 | ALA5131517 | single protein format | Scientific Literature | |
12. | ALA5135850 | B | Binding affinity to 5HT7 receptor (unknown origin) assessed as inhibition constant | Homo sapiens | 4 | ALA5131517 | single protein format | Scientific Literature | |
13. | ALA5135852 | B | Inhibition of alpha2c (unknown origin) | Homo sapiens | 3 | ALA5131517 | single protein format | Scientific Literature | |
14. | ALA5135854 | B | Binding affinity to beta1 receptor (unknown origin) assessed as inhibition constant | Homo sapiens | 2 | ALA5131517 | single protein format | Scientific Literature | |
15. | ALA5135856 | B | Inhibition of D3 receptor (unknown origin) | Homo sapiens | 3 | ALA5131517 | single protein format | Scientific Literature | |
16. | ALA5135858 | B | Inhibition of D4 receptor (unknown origin) | Homo sapiens | 2 | ALA5131517 | single protein format | Scientific Literature | |
17. | ALA5135860 | B | Inhibition of SERT receptor (unknown origin) | Homo sapiens | 3 | ALA5131517 | single protein format | Scientific Literature | |
18. | ALA5135861 | B | Binding affinity to sigma 1 receptor (unknown origin) assessed as inhibition constant | Homo sapiens | 3 | ALA5131517 | single protein format | Scientific Literature | |
19. | ALA5135863 | B | Binding affinity to 5HT2B receptor (unknown origin) assessed as inhibition constant | Homo sapiens | 4 | ALA5131517 | single protein format | Scientific Literature | |
20. | ALA5135864 | B | Binding affinity to 5HT2A receptor (unknown origin) assessed as inhibition constant | Homo sapiens | 4 | ALA5131517 | single protein format | Scientific Literature |