| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5162749 | B | Binding affinity to beta-tubulin colchicine binding site in human HeLa cells assessed as decrease of adduct formation by measuring gray value measured at 25 uM incubated for 2 hrs followed by addition of EBI measured after 1.5 hrs by EBI competition based Western blotting analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 2. | ALA5162750 | F | Antiproliferation activity against human HeLa cells assessed as reduction in cell growth measured after 48 to 72 hrs by CCK-8 assay | Homo sapiens | 23 | cell-based format | Scientific Literature | ||
| 3. | ALA5162751 | F | Antiproliferation activity against human SiHa cells assessed as reduction in cell growth measured after 48 to 72 hrs by CCK-8 assay | Homo sapiens | 23 | cell-based format | Scientific Literature | ||
| 4. | ALA5162752 | F | Antiproliferation activity against human MS751 cells assessed as reduction in cell growth measured after 48 to 72 hrs by CCK-8 assay | Homo sapiens | 23 | cell-based format | Scientific Literature | ||
| 5. | ALA5162756 | B | Inhibition of pig brain tubulin polymerization by spectrophotometeric analysis | Sus scrofa domesticus | 14 | assay format | Scientific Literature | ||
| 6. | ALA5162757 | B | Binding affinity to beta-tubulin colchicine binding site in human HeLa cells assessed as inhibition of EBI-beta-tubulin adduct formation measured at 1 to 100 uM incubated for 2 hrs followed by addition of EBI measured after 1.5 hrs by EBI competition based Western blotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA5162759 | B | Inhibition of pig brain tubulin polymerization at 3 uM by spectrophotometer analysis relative to control | Sus scrofa domesticus | 1 | assay format | Scientific Literature | ||
| 8. | ALA5162760 | B | Inhibition of pig brain tubulin polymerization at 6 uM by spectrophotometer analysis relative to control | Sus scrofa domesticus | 1 | assay format | Scientific Literature | ||
| 9. | ALA5162761 | B | Inhibition of pig brain tubulin polymerization at 12.5 uM by spectrophotometer analysis relative to control | Sus scrofa domesticus | 1 | assay format | Scientific Literature | ||
| 10. | ALA5162763 | B | Induction of microtubule disruption in human HeLa cells assessed as loss of cellular structure at 0.1 to 0.2 uM measured after 24 hrs by DAPI staining based laser scanning confocal microscopic analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA5162764 | B | Induction of microtubule disruption in human HeLa cells assessed as loss of formation of cell membrane rounding at 0.1 to 0.2 uM measured after 24 hrs by DAPI staining based laser scanning confocal microscopic analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA5162767 | F | Induction of cell cycle arrest in human HeLa cells assessed as < 2N cells at 0.1 uM measured after 24 hrs by propidium iodide staining based flow cytometric analysis analysis ( Rvb = 7.07%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA5162768 | F | Induction of cell cycle arrest in human HeLa cells assessed as < 2N cells at 0.2 uM measured after 24 hrs by propidium iodide staining based flow cytometric analysis analysis ( Rvb = 7.07%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA5162769 | F | Induction of cell cycle arrest in human HeLa cells assessed as < 2N cells at 0.4 uM measured after 24 hrs by propidium iodide staining based flow cytometric analysis analysis ( Rvb = 7.07%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA5162773 | F | Induction of cell cycle arrest in human HeLa cells assessed as 2N cells at 0.1 uM measured after 24 hrs by propidium iodide staining based flow cytometric analysis analysis ( Rvb = 47.4%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA5162774 | F | Induction of cell cycle arrest in human HeLa cells assessed as 2N cells at 0.2 uM measured after 24 hrs by propidium iodide staining based flow cytometric analysis analysis ( Rvb = 47.4%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA5162775 | F | Induction of cell cycle arrest in human HeLa cells assessed as 2N cells at 0.4 uM measured after 24 hrs by propidium iodide staining based flow cytometric analysis analysis ( Rvb = 47.4%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA5162779 | F | Induction of cell cycle arrest in human HeLa cells assessed as S-phase at 0.1 uM measured after 24 hrs by propidium iodide staining based flow cytometric analysis analysis ( Rvb = 15.5%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA5162780 | F | Induction of cell cycle arrest in human HeLa cells assessed as S-phase at 0.2 uM measured after 24 hrs by propidium iodide staining based flow cytometric analysis analysis ( Rvb = 15.5%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA5162781 | F | Induction of cell cycle arrest in human HeLa cells assessed as S-phase at 0.4 uM measured after 24 hrs by propidium iodide staining based flow cytometric analysis analysis ( Rvb = 15.5%) | Homo sapiens | 1 | cell-based format | Scientific Literature |
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