# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5135071 | Toxicity | Cytotoxicity against human MRC5 fibroblast cells assessed as reduction in cell viability measured after 3 days by fluorometry | Homo sapiens | 29 | ALA5131491 | cell-based format | Scientific Literature | |
2. | ALA5135073 | Functional | Antitrypanosomal activity against intracellular Trypanosoma cruzi Tulahuen amastigotes expressing CL2 beta-galactosidase in human MRC5 cells assessed as parasite growth inhibition using chlorophenol red beta-D-galactopyranoside as substrate treated for 7 days by spectrophotometry | Trypanosoma cruzi | 30 | ALA5131491 | organism-based format | Scientific Literature | |
3. | ALA5135074 | Toxicity | Selectivity index, ratio of CC50 for human MRC-5 cells to EC50 for antitrypanosomal activity against intracellular Trypanosoma cruzi Tulahuen amastigotes expressing CL2 beta-galactosidase in human MRC5 cells | 21 | ALA5131491 | cell-based format | Scientific Literature | ||
4. | ALA5135075 | Functional | Antileishmanial activity against intracellular Leishmania infantum MHOM/MA(BE)/67 amastigotes infected in Swiss mouse peritoneal macrophages assessed as parasite growth inhibition incubated for 5 days by giemsa staining based microscopic analysis | Leishmania infantum | 30 | ALA5131491 | organism-based format | Scientific Literature | |
5. | ALA5135076 | Toxicity | Cytotoxicity against Swiss mouse peritoneal macrophages assessed as reduction in cell viability measured after 5 days by microscopic analysis | Mus musculus | 29 | ALA5131491 | cell-based format | Scientific Literature |