# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5166787 | Binding | Agonist activity at wild type human TR alpha LBD expressed in Escherichia coli BL21 (DE3) assessed as induction of N-terminal biotinylated coactivator SRC2-3 peptide recruitment by alphascreen assay | Homo sapiens | 28 | ALA5154903 | assay format | Scientific Literature | |
2. | ALA5166788 | Binding | Agonist activity at human TR beta LBD (202 to 461 residues) expressed in Escherichia coli BL21 (DE3) cells assessed as induction of N-terminal biotinylated coactivator SRC2-3 peptide recruitment by alphascreen assay | Homo sapiens | 32 | ALA5154903 | cell-based format | Scientific Literature | |
3. | ALA5166792 | Binding | Selectivity ratio of EC50 for agonist activity at wild type human TR alpha LBD expressed in Escherichia coli BL21 (DE3) to EC50 for agonist activity at human TR beta LBD (202 to 461 residues) expressed in Escherichia coli BL21 (DE3) cells | Homo sapiens | 14 | ALA5154903 | cell-based format | Scientific Literature |