| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5118101 | B | Protac activity at CRBN/PARP1 in human MDA-MB-231 cells assessed as PARP1 degradation measured after 24 hrs | Homo sapiens | 1 | ALA5113490 | cell-based format | Scientific Literature | |
| 2. | ALA5118102 | B | Protac activity at CRBN/PARP1 in human MDA-MB-231 cells assessed as PARP1 degradation at 10 uM measured after 4 to 48 hrs | Homo sapiens | 1 | ALA5113490 | cell-based format | Scientific Literature | |
| 3. | ALA5118103 | B | Binding affinity to CRBN in human MDA-MB-231 cells measured by thermal shift assay | Homo sapiens | 1 | ALA5113490 | cell-based format | Scientific Literature | |
| 4. | ALA5118104 | B | Protac activity at CRBN/PARP1 in human MDA-MB-231 cells assessed as PARP1 degradation at 10 uM measured after 12 hrs in presence of 10 uM niraparib by thermal shift assay | Homo sapiens | 1 | ALA5113490 | cell-based format | Scientific Literature | |
| 5. | ALA5118105 | B | Protac activity at CRBN/PARP1 in human MDA-MB-231 cells assessed as PARP1 degradation at 10 uM measured after 12 hrs in presence of 10 uM pomalidomide by thermal shift assay | Homo sapiens | 1 | ALA5113490 | cell-based format | Scientific Literature | |
| 6. | ALA5118106 | B | Protac activity at CRBN/PARP1 in human MDA-MB-231 cells assessed as PARP1 degradation at 10 uM measured after 12 hrs in presence of 10 uM pomalidomide and 10 uM niraparib by thermal shift assay | Homo sapiens | 1 | ALA5113490 | cell-based format | Scientific Literature | |
| 7. | ALA5118107 | B | Protac activity at CRBN/PARP1 in human MDA-MB-231 cells assessed as PARP1 degradation at 10 uM measured after 12 hrs in presence of 1 uM MLN4924 by thermal shift assay | Homo sapiens | 1 | ALA5113490 | cell-based format | Scientific Literature | |
| 8. | ALA5118108 | B | Protac activity at CRBN/PARP1 in human MDA-MB-231 cells assessed as PARP1 degradation at 10 uM measured after 12 hrs in presence of 1 uM MG132 by thermal shift assay | Homo sapiens | 1 | ALA5113490 | cell-based format | Scientific Literature | |
| 9. | ALA5118109 | B | Protac activity at CRBN/PARP1 in human MDA-MB-231 cells assessed as change in PARP1 mRNA level at 2 to 25 uM measured after 12 hrs by qRT-PCR assay | Homo sapiens | 1 | ALA5113490 | cell-based format | Scientific Literature | |
| 10. | ALA5118110 | B | Protac activity at CRBN/PARP1 in human MDA-MB-231 cells assessed as PARP1 degradation at 10 uM measured after 3 hrs in presence of 10 uM Z-VAD-FMK | Homo sapiens | 1 | ALA5113490 | cell-based format | Scientific Literature | |
| 11. | ALA5118111 | F | Inhibition of DNA repair in human MDA-MB-231 cells assessed as induction of gamma-H2AX level at 10 uM in presence of 0.5 uM daunorubicin measured after 2 hrs by western blot analysis | Homo sapiens | 1 | ALA5113490 | cell-based format | Scientific Literature | |
| 12. | ALA5118112 | F | Inhibition of DNA repair in human MDA-MB-231 cells assessed as induction of free cytosolic dsDNA at 5 uM in presence of 0.5 uM daunorubicin measured after 24 hrs by DAPI staining method | Homo sapiens | 1 | ALA5113490 | cell-based format | Scientific Literature | |
| 13. | ALA5118113 | F | Growth inhibition of human MDA-MB-231 cells at 10 uM | Homo sapiens | 1 | ALA5113490 | cell-based format | Scientific Literature | |
| 14. | ALA5118117 | F | Growth inhibition of human MDA-MB-231 cells at 10 uM in presence of 0.25 uM daunorubicin | Homo sapiens | 1 | ALA5113490 | cell-based format | Scientific Literature | |
| 15. | ALA5118118 | F | Growth inhibition of human MDA-MB-231 cells at 10 uM in presence of 1 uM daunorubicin | Homo sapiens | 1 | ALA5113490 | cell-based format | Scientific Literature | |
| 16. | ALA5118119 | F | Growth inhibition of human MDA-MB-231 cells at 10 uM in presence of 4 uM daunorubicin | Homo sapiens | 1 | ALA5113490 | cell-based format | Scientific Literature | |
| 17. | ALA5118120 | F | Growth inhibition of human MDA-MB-231 cells assessed as combination index at 10 uM in presence of 0.25 uM daunorubicin | Homo sapiens | 1 | ALA5113490 | cell-based format | Scientific Literature | |
| 18. | ALA5118121 | F | Growth inhibition of human MDA-MB-231 cells assessed as combination index at 10 uM in presence of 1 uM daunorubicin | Homo sapiens | 1 | ALA5113490 | cell-based format | Scientific Literature | |
| 19. | ALA5118122 | F | Growth inhibition of human MDA-MB-231 cells assessed as combination index at 10 uM in presence of 4 uM daunorubicin | Homo sapiens | 1 | ALA5113490 | cell-based format | Scientific Literature | |
| 20. | ALA5118123 | F | Growth inhibition of mouse 4T1 cells at 10 uM | Mus musculus | 1 | ALA5113490 | cell-based format | Scientific Literature |
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