# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5098382 | B | Inhibition of BTK (unknown origin) incubated 30 mins by FRET assay | Homo sapiens | 50 | single protein format | Scientific Literature | ||
2. | ALA5098387 | T | Antiproliferative activity against human PBMC preincubated for 30 mins followed by IL-4 stimulation for 3 days by cell titer glo assay | Homo sapiens | 27 | cell-based format | Scientific Literature | ||
3. | ALA5098391 | A | Metabolic stability in rat liver microsomes assessed as hepatic blood flow | Rattus norvegicus | 2 | microsome format | Scientific Literature | ||
4. | ALA5098392 | A | Metabolic stability in human liver microsomes assessed as hepatic blood flow | Homo sapiens | 2 | microsome format | Scientific Literature | ||
5. | ALA5098393 | B | Binding affinity to human full length BTK C481S mutation (M1 to S659 residues ) expressed in mammalian expression system assessed dissociation constant by Kinomescan method | Homo sapiens | 6 | assay format | Scientific Literature | ||
6. | ALA5098395 | B | Binding affinity to human partial length ITK (R335 to L620 residues ) expressed in bacterial expression system assessed dissociation constant by Kinomescan method | Homo sapiens | 7 | assay format | Scientific Literature | ||
7. | ALA5098396 | B | Binding affinity to human partial length TXK (L238 to W527 residues ) expressed in bacterial expression system assessed dissociation constant by Kinomescan method | Homo sapiens | 7 | assay format | Scientific Literature | ||
8. | ALA5098397 | B | Binding affinity to human full length BMX (M1 to H675 residues ) expressed in bacterial expression system assessed dissociation constant by Kinomescan method | Homo sapiens | 7 | assay format | Scientific Literature | ||
9. | ALA5098402 | B | Inhibition of CD69 (unknown origin) in PBMC preincubated for 30 mins followed by IL-4 stimulation for 3 days by cell titer glo assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
10. | ALA5098403 | P | Lipophilicity, logD of compound | 2 | small-molecule physicochemical format | Scientific Literature | |||
11. | ALA5098404 | P | Kinetic solubility of compound at pH 6.8 | 2 | small-molecule physicochemical format | Scientific Literature | |||
12. | ALA5098405 | A | Plasma protein binding in human assessed as unbound fraction at 2 uM by rapid equilibrium dialysis analysis | Homo sapiens | 3 | cell-free format | Scientific Literature | ||
13. | ALA5098406 | A | Plasma protein binding in rat assessed as unbound fraction at 2 uM by rapid equilibrium dialysis analysis | Rattus norvegicus | 3 | cell-free format | Scientific Literature |