| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5153189 | Functional | Antiproliferative activity against human NALM-6 cells assessed as reduction in cell viability incubated for 48 hrs by CCK8 assay | Homo sapiens | 7 | ALA5150047 | cell-based format | Scientific Literature | |
| 2. | ALA5153190 | Functional | Antiproliferative activity against human Jurkat cells assessed as reduction in cell viability incubated for 48 hrs by CCK8 assay | Homo sapiens | 6 | ALA5150047 | cell-based format | Scientific Literature | |
| 3. | ALA5153191 | Functional | Antiproliferative activity against human HL-60 cells assessed as reduction in cell viability incubated for 48 hrs by CCK8 assay | Homo sapiens | 6 | ALA5150047 | cell-based format | Scientific Literature | |
| 4. | ALA5153192 | Functional | Antiproliferative activity against human K562 cells assessed as reduction in cell viability incubated for 48 hrs by CCK8 assay | Homo sapiens | 6 | ALA5150047 | cell-based format | Scientific Literature | |
| 5. | ALA5153193 | Functional | Potency index, ratio of celecoxib IC50 to test compound IC50 for antiproliferative activity against human NALM-6 cells assessed as reduction in cell viability incubated for 48 hrs by CCK8 assay | Homo sapiens | 1 | ALA5150047 | cell-based format | Scientific Literature | |
| 6. | ALA5153194 | Functional | Antiproliferative activity against human NALM-6 cells assessed as reduction in cell viability incubated for 24 hrs by CCK8 assay | Homo sapiens | 1 | ALA5150047 | cell-based format | Scientific Literature | |
| 7. | ALA5153196 | Toxicity | Cytotoxicity against human L02 cells assessed as reduction in cell viability by CCK8 assay | Homo sapiens | 2 | ALA5150047 | cell-based format | Scientific Literature | |
| 8. | ALA5153197 | Toxicity | Cytotoxicity against human MCF-10A cells assessed as reduction in cell viability by CCK8 assay | Homo sapiens | 2 | ALA5150047 | cell-based format | Scientific Literature | |
| 9. | ALA5153198 | Binding | Inhibition of HDAC in human NALM-6 nuclear extract incubated for 48 hrs by fluorometric analysis | Homo sapiens | 1 | ALA5150047 | subcellular format | Scientific Literature | |
| 10. | ALA5153199 | Functional | Downregulation of HDAC2 expression in human NALM-6 cells incubated for 48 hrs by western blot analysis | Homo sapiens | 1 | ALA5150047 | cell-based format | Scientific Literature | |
| 11. | ALA5153200 | Functional | Downregulation of HDAC1 expression in human NALM-6 cells at 10 to 30 uM incubated for 48 hrs by western blot analysis | Homo sapiens | 1 | ALA5150047 | cell-based format | Scientific Literature | |
| 12. | ALA5153201 | Binding | Inhibition of COX-2 in human NALM-6 cells assessed as downregulation of COX-2 expression by measuring COX-2 expression at 10 to 30 uM incubated for 48 hrs by DAPI staining based immunofluorescence based analysis relative to control | Homo sapiens | 2 | ALA5150047 | cell-based format | Scientific Literature | |
| 13. | ALA5153202 | Functional | Induction of cell cycle arrest in human NALM-6 cells assessed as accumulation of cells at G2 phase at 30 uM incubated for 48 hrs by PI/RNase staining based flow cytometry | Homo sapiens | 1 | ALA5150047 | cell-based format | Scientific Literature | |
| 14. | ALA5153203 | Functional | Induction of cell cycle arrest in human NALM-6 cells assessed as reduction in proportion of cells at S phase at 30 uM incubated for 48 hrs by PI/RNase staining based flow cytometry | Homo sapiens | 1 | ALA5150047 | cell-based format | Scientific Literature | |
| 15. | ALA5153204 | Functional | Induction of apoptosis in human NALM-6 cells assessed as viable cells at 10 uM incubated for 48 hrs by AnnexinV-FITC/PI staining based flow cytometry (Rvb = 97.98%) | Homo sapiens | 1 | ALA5150047 | cell-based format | Scientific Literature | |
| 16. | ALA5153205 | Functional | Induction of apoptosis in human NALM-6 cells assessed as early apoptotic cells at 10 uM incubated for 48 hrs by AnnexinV-FITC/PI staining based flow cytometry (Rvb = 1.09%) | Homo sapiens | 1 | ALA5150047 | cell-based format | Scientific Literature | |
| 17. | ALA5153206 | Functional | Induction of apoptosis in human NALM-6 cells assessed as late apoptotic cells at 10 uM incubated for 48 hrs by AnnexinV-FITC/PI staining based flow cytometry (Rvb = 0.92%) | Homo sapiens | 1 | ALA5150047 | cell-based format | Scientific Literature | |
| 18. | ALA5153207 | Functional | Induction of apoptosis in human NALM-6 cells assessed as necrotic cells at 10 uM incubated for 48 hrs by AnnexinV-FITC/PI staining based flow cytometry (Rvb = 0.01%) | Homo sapiens | 1 | ALA5150047 | cell-based format | Scientific Literature | |
| 19. | ALA5153208 | Functional | Induction of apoptosis in human NALM-6 cells assessed as viable cells at 30 uM incubated for 48 hrs by AnnexinV-FITC/PI staining based flow cytometry (Rvb = 97.98%) | Homo sapiens | 1 | ALA5150047 | cell-based format | Scientific Literature | |
| 20. | ALA5153209 | Functional | Induction of apoptosis in human NALM-6 cells assessed as early apoptotic cells at 30 uM incubated for 48 hrs by AnnexinV-FITC/PI staining based flow cytometry (Rvb = 1.09%) | Homo sapiens | 1 | ALA5150047 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!