# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5129286 | B | Inhibition of human TRPC5 channel expressed in HEK293 cells assessed as inhibition of EA-evoked Calcium influx by measuring reduction in intracellular Ca2+ level and measured upto 360 sec by Fluo-4/AM dye based FLIPR assay | Homo sapiens | 36 | cell-based format | Scientific Literature | ||
2. | ALA5129287 | B | Inhibition of human TRPC4 channel expressed in HEK293 cells assessed as inhibition of EA-evoked Calcium influx by measuring reduction in intracellular Ca2+ level and measured upto 360 sec by Fluo-4/AM dye based FLIPR assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
3. | ALA5129288 | F | Protective effect against protamine sulfate induced cytoskeleton rearrangement in mouse MPC-5 cell assessed as reduction in aggregated stress fibers at 1 to 3 uM pretreatment followed by PS stimulation and measured after 2 hrs by phalloidin and Hoechst 33342 staining based fluorescence analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
4. | ALA5129290 | F | Inhibition of IL-17 induced cell proliferation in human HaCaT cells assessed as decrease in BrdU positive (BrdU+) cells at 0.3 to 3 uM and measured after 24 hrs by BrdU incorporation assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
5. | ALA5129292 | F | Inhibition of IL-17 induced inflammation in human HaCaT cells assessed as reduction in IL-6 mRNA level at 0.3 to 3 uM by qRT-PCR analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
6. | ALA5129293 | F | Inhibition of IL-17 induced inflammation in human HaCaT cells assessed as reduction in IL-8 mRNA level at 0.3 to 3 uM by qRT-PCR analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
7. | ALA5129294 | F | Inhibition of IL-17 induced inflammation in human HaCaT cells assessed as reduction in CCL-20 mRNA level at 0.3 to 3 uM by qRT-PCR analysis | Homo sapiens | 1 | cell-based format | Scientific Literature |