| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5121790 | Toxicity | Cytotoxicity against mouse NIH/3T3 cells overexpressing FGFR3 S249C assessed as cell growth inhibition incubated for 5 days by CellTitre-Glo assay | Mus musculus | 14 | ALA5120772 | cell-based format | Scientific Literature | |
| 2. | ALA5121791 | ADME | Intrinsic clearance in human liver microsomes | Homo sapiens | 15 | ALA5120772 | microsome format | Scientific Literature | |
| 3. | ALA5121793 | Physicochemical | Lipophilicity, logD of the compound in 1-octanol and phosphate buffer at pH 7.4 by LC-MS analysis | 14 | ALA5120772 | small-molecule physicochemical format | Scientific Literature | ||
| 4. | ALA5121794 | ADME | Permeability of the compound in aqueous buffer at pH 6.5 incubated for 2 hrs by PAMPA based HPLC analysis | 14 | ALA5120772 | assay format | Scientific Literature | ||
| 5. | ALA5121856 | Binding | Inhibition of wild type N-terminal GST tagged FGFR3 (436 to 806 residues) (unknown origin) expressed in sf21 insect cells preincubated for 30 mins followed by substrate addition and measured after 30 mins in presence of ATP by off-chip mobility shift assay | Homo sapiens | 14 | ALA5120772 | cell-based format | Scientific Literature |
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