# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5143815 | Toxicity | Cytotoxicity against human GES1 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay | Homo sapiens | 14 | ALA5143508 | cell-based format | Scientific Literature | |
2. | ALA5143816 | Functional | Cytotoxicity against human SGC-7901 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay | Homo sapiens | 14 | ALA5143508 | cell-based format | Scientific Literature | |
3. | ALA5143817 | Functional | Cytotoxicity against human AGS cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay | Homo sapiens | 14 | ALA5143508 | cell-based format | Scientific Literature | |
4. | ALA5143818 | Functional | Cytotoxicity against human BGC-823 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay | Homo sapiens | 14 | ALA5143508 | cell-based format | Scientific Literature | |
5. | ALA5143819 | Functional | Cytotoxicity against human MGC-803 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay | Homo sapiens | 14 | ALA5143508 | cell-based format | Scientific Literature | |
6. | ALA5143820 | Functional | Induction of cell cycle arrest in human HGC-27 cells assessed as downregulation of CDK2 expression incubated for 48 hrs by Western blot analysis | Homo sapiens | 2 | ALA5143508 | cell-based format | Scientific Literature | |
7. | ALA5143821 | Toxicity | Acute toxicity in Kunming mouse assessed as mouse survival at 1000 mg/kg, po measured after 14 days | Mus musculus | 1 | ALA5143508 | organism-based format | Scientific Literature | |
8. | ALA5143822 | ADME | Half life in Sprague-Dawley rat at 100 mg/kg, po measured up to 24 hrs by LC-MS/MS analysis | Rattus norvegicus | 2 | ALA5143508 | organism-based format | Scientific Literature | |
9. | ALA5143823 | Functional | Anti-invasion activity against human HGC-27 cells assessed as inhibition of invasion incubated for 24 hrs by transwell invasion assay | Homo sapiens | 2 | ALA5143508 | cell-based format | Scientific Literature | |
10. | ALA5143824 | Functional | Cytotoxicity against human HGC-27 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay | Homo sapiens | 14 | ALA5143508 | cell-based format | Scientific Literature | |
11. | ALA5143825 | Toxicity | Cytotoxicity against human WI-38 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay | Homo sapiens | 12 | ALA5143508 | cell-based format | Scientific Literature | |
12. | ALA5143826 | Functional | Induction of morphological changes in human HGC-27 cells assessed as cytomembrane foaming incubated for 36 hrs by Giemsa staining based microscopic analysis | Homo sapiens | 2 | ALA5143508 | cell-based format | Scientific Literature | |
13. | ALA5143827 | Functional | Induction of morphological changes in human HGC-27 cells assessed as chromatin condensation incubated for 36 hrs by Giemsa staining based microscopic analysis | Homo sapiens | 2 | ALA5143508 | cell-based format | Scientific Literature | |
14. | ALA5143828 | Functional | Induction of morphological changes in human MGC-803 cells assessed as cytomembrane foaming incubated for 36 hrs by Giemsa staining based microscopic analysis | Homo sapiens | 2 | ALA5143508 | cell-based format | Scientific Literature | |
15. | ALA5143829 | Functional | Induction of morphological changes in human MGC-803 cells assessed as chromatin condensation incubated for 36 hrs by Giemsa staining based microscopic analysis | Homo sapiens | 2 | ALA5143508 | cell-based format | Scientific Literature | |
16. | ALA5143830 | Functional | Induction of apoptosis in human HGC-27 cells assessed as viable cells at 0.1 uM incubated for 48 hrs by annexin V FITC/propidium iodide staining based flow cytometry (Rvb = 93.0 %) | Homo sapiens | 1 | ALA5143508 | cell-based format | Scientific Literature | |
17. | ALA5143831 | Functional | Induction of apoptosis in human HGC-27 cells assessed as early apoptotic cells at 0.1 uM incubated for 48 hrs by annexin V FITC/propidium iodide staining based flow cytometry (Rvb = 0.66 %) | Homo sapiens | 1 | ALA5143508 | cell-based format | Scientific Literature | |
18. | ALA5143832 | Functional | Induction of apoptosis in human HGC-27 cells assessed as late apoptotic cells at 0.1 uM incubated for 48 hrs by annexin V FITC/propidium iodide staining based flow cytometry (Rvb = 5.14 %) | Homo sapiens | 1 | ALA5143508 | cell-based format | Scientific Literature | |
19. | ALA5143833 | Functional | Induction of apoptosis in human HGC-27 cells assessed as necrotic cells at 0.1 uM incubated for 48 hrs by annexin V FITC/propidium iodide staining based flow cytometry (Rvb = 1.24 %) | Homo sapiens | 1 | ALA5143508 | cell-based format | Scientific Literature | |
20. | ALA5143834 | Functional | Induction of apoptosis in human HGC-27 cells assessed as viable cells at 0.4 uM incubated for 48 hrs by annexin V FITC/propidium iodide staining based flow cytometry (Rvb = 93.0 %) | Homo sapiens | 1 | ALA5143508 | cell-based format | Scientific Literature |