# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5110078 | F | Antiproliferative activity against EML4-ALK-positive human NCI-H3122 cells incubated for 72 hrs and measured by CCK-8 assay | Homo sapiens | 31 | cell-based format | Scientific Literature | ||
2. | ALA5110079 | F | Antiproliferative activity against EML4-ALK-positive human NCI-H2228 cells incubated for 72 hrs and measured by CCK-8 assay | Homo sapiens | 31 | cell-based format | Scientific Literature | ||
3. | ALA5110080 | F | Antiproliferative activity against NPM-ALK-positive human KARPAS-299 cells incubated for 72 hrs and measured by CCK-8 assay | Homo sapiens | 31 | cell-based format | Scientific Literature | ||
4. | ALA5110081 | F | Antiproliferative activity against EGFR-positive human A549 cells incubated for 72 hrs and measured by CCK-8 assay | Homo sapiens | 31 | cell-based format | Scientific Literature | ||
5. | ALA5110082 | U | Selectivity index, ratio IC50 for antiproliferative activity against EGFR-positive human A549 cells to IC50 for antiproliferative activity against EML4-ALK-positive human NCI-H3122 cells | 31 | assay format | Scientific Literature | |||
6. | ALA5110083 | U | Selectivity index, ratio IC50 for antiproliferative activity against EGFR-positive human A549 cells to IC50 for antiproliferative activity against EML4-ALK-positive human NCI-H2228 cells | 31 | assay format | Scientific Literature | |||
7. | ALA5110084 | U | Selectivity index, ratio IC50 for antiproliferative activity against EGFR-positive human A549 cells to IC50 for antiproliferative activity against NPM-ALK-positive human KARPAS-299 cells | 31 | assay format | Scientific Literature | |||
8. | ALA5110085 | B | Inhibition of ALK (unknown origin) incubated for 1 hr and measured by mobility shift assay | Homo sapiens | 6 | single protein format | Scientific Literature | ||
9. | ALA5110086 | B | Inhibition of ALK L1196M mutant (unknown origin) incubated for 1 hr and measured by mobility shift assay | Homo sapiens | 6 | single protein format | Scientific Literature | ||
10. | ALA5110087 | B | Inhibition of ALK G1202R mutant (unknown origin) incubated for 1 hr and measured by mobility shift assay | Homo sapiens | 6 | single protein format | Scientific Literature | ||
11. | ALA5110088 | B | Inhibition of EGFR (unknown origin) incubated for 1 hr and measured by mobility shift assay | Homo sapiens | 6 | single protein format | Scientific Literature | ||
12. | ALA5110089 | F | Antiproliferative activity against human NCI-H460 cells incubated for 72 hrs and measured by CCK-8 assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
13. | ALA5110090 | F | Antiproliferative activity against human NCI-H1581 cells incubated for 72 hrs and measured by CCK-8 assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
14. | ALA5110091 | F | Antiproliferative activity against human MCF7 cells incubated for 72 hrs and measured by CCK-8 assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
15. | ALA5110092 | F | Antiproliferative activity against human HCT-116 cells incubated for 72 hrs and measured by CCK-8 assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
16. | ALA5110093 | F | Antiproliferative activity against human PC-3 cells incubated for 72 hrs and measured by CCK-8 assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
17. | ALA5110094 | T | Cytotoxicity against human HELF cells incubated for 72 hrs and measured by CCK-8 assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
18. | ALA5110095 | F | Antiproliferative activity against EML4-ALK-positive human NCI-H2228 cells incubated for 3 days at 25 to 100 nM and assessed as decrease in number of colonies by colony formation assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
19. | ALA5110096 | F | Inhibition of cell migration in EML4-ALK-positive human NCI-H2228 cells assessed as relative migration rate at 5 nM measured after 24 hrs by cell scratch assay (Rvb = 21.4 %) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
20. | ALA5110097 | F | Inhibition of cell migration in EML4-ALK-positive human NCI-H2228 cells assessed as relative migration rate at 10 nM measured after 24 hrs by cell scratch assay (Rvb = 21.4 %) | Homo sapiens | 1 | cell-based format | Scientific Literature |