| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5130015 | B | Antagonist activity at human TLR9 expressed in HEK-blue hTLR9 cells assessed as inhibition of CpGB-induced NFkappaB activation preincubated with compound for 1 hrs followed by CpGB addition and measured next day by SEAP-based spectrophotometry assay | Homo sapiens | 40 | cell-based format | Scientific Literature | ||
| 2. | ALA5130017 | B | Antagonist activity at human TLR7 expressed in HEK-blue hTLR7 cells assessed as inhibition of CL264-induced NFkappaB activation preincubated with compound for 1 hrs followed by CL264 addition and measured next day by SEAP-based spectrophotometry assay | Homo sapiens | 40 | cell-based format | Scientific Literature | ||
| 3. | ALA5130023 | B | Antagonist activity at human TLR8 expressed in HEK-blue hTLR8 cells assessed as inhibition of CL075-induced NFkappaB activation at 20 uM preincubated with compound for 1 hrs followed by CL075 addition and measured next day by SEAP-based spectrophotometry assay | Homo sapiens | 8 | cell-based format | Scientific Literature |
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