| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5115322 | B | Inhibition of wild type Bcr-Abl (unknown origin) incubated for 1 hr in presence of ATP by ADP-Glo kinase assay | Homo sapiens | 41 | ALA5113400 | protein format | Scientific Literature | |
| 2. | ALA5115323 | B | Inhibition of Bcr-Abl T315I mutant (unknown origin) incubated for 1 hr in presence of ATP by ADP-Glo kinase assay | Homo sapiens | 41 | ALA5113400 | protein format | Scientific Literature | |
| 3. | ALA5115324 | B | Selectivity ratio of IC50 for inhibition of Bcr-Abl T315I mutant (unknown origin) to IC50 for inhibition of wild type Bcr-Abl (unknown origin) | Homo sapiens | 41 | ALA5113400 | assay format | Scientific Literature | |
| 4. | ALA5115325 | F | Antiproliferative activity against human K562 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay | Homo sapiens | 41 | ALA5113400 | cell-based format | Scientific Literature | |
| 5. | ALA5115326 | F | Antiproliferative activity against mouse BaF3 cells expressing Bcr-Abl T315I mutant assessed as inhibition of cell growth at 30 uM incubated for 72 hrs by CellTiter-Glo luminescent assay | Mus musculus | 31 | ALA5113400 | cell-based format | Scientific Literature | |
| 6. | ALA5115327 | F | Antiproliferative activity against human Adriamycin-resistant K562/Adr cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay | Homo sapiens | 13 | ALA5113400 | cell-based format | Scientific Literature | |
| 7. | ALA5115329 | F | Antiproliferative activity against human K-562R cells expressing Bcr-Abl T315I mutant assessed as inhibition of cell growth incubated for 48 hrs by MTT assay | Homo sapiens | 5 | ALA5113400 | cell-based format | Scientific Literature | |
| 8. | ALA5115330 | T | Cytotoxicity against human HEK293 cells assessed as inhibition of cell growth upto 100 uM incubated for 48 hrs by MTT assay | Homo sapiens | 3 | ALA5113400 | cell-based format | Scientific Literature | |
| 9. | ALA5115331 | T | Cytotoxicity against human EA.hy 926 cells assessed as inhibition of cell growth upto 100 uM incubated for 48 hrs by MTT assay | Homo sapiens | 3 | ALA5113400 | cell-based format | Scientific Literature | |
| 10. | ALA5115332 | F | Antiproliferative activity against mouse BaF3 cells expressing wild type Bcr-Abl assessed as inhibition of cell growth incubated for 72 hrs by CellTiter-Glo luminescent assay | Mus musculus | 4 | ALA5113400 | cell-based format | Scientific Literature | |
| 11. | ALA5115333 | F | Antiproliferative activity against mouse BaF3 cells expressing Bcr-Abl T315I mutant assessed as inhibition of cell growth incubated for 72 hrs by CellTiter-Glo luminescent assay | Mus musculus | 4 | ALA5113400 | cell-based format | Scientific Literature | |
| 12. | ALA5115334 | F | Antiproliferative activity against mouse BaF3 cells assessed as inhibition of cell growth incubated for 72 hrs by CellTiter-Glo luminescent assay | Mus musculus | 4 | ALA5113400 | cell-based format | Scientific Literature | |
| 13. | ALA5115349 | F | Induction of apoptosis in human K562 cells assessed as necrotic cells at 1 uM incubated for 48 hrs by Annexin V-FITC/PI staining based flow cytometry analysis (Rvb= 0.29%) | Homo sapiens | 1 | ALA5113400 | cell-based format | Scientific Literature | |
| 14. | ALA5115350 | F | Induction of apoptosis in human K562 cells assessed as necrotic cells at 5 uM incubated for 48 hrs by Annexin V-FITC/PI staining based flow cytometry analysis (Rvb= 0.29%) | Homo sapiens | 1 | ALA5113400 | cell-based format | Scientific Literature | |
| 15. | ALA5115351 | F | Induction of apoptosis in human K562 cells assessed as necrotic cells at 10 uM incubated for 48 hrs by Annexin V-FITC/PI staining based flow cytometry analysis (Rvb= 0.29%) | Homo sapiens | 1 | ALA5113400 | cell-based format | Scientific Literature | |
| 16. | ALA5115352 | F | Induction of apoptosis in human K562 cells assessed as early apoptotic cells at 1 uM incubated for 48 hrs by Annexin V-FITC/PI staining based flow cytometry analysis (Rvb= 16.26%) | Homo sapiens | 1 | ALA5113400 | cell-based format | Scientific Literature | |
| 17. | ALA5115353 | F | Induction of apoptosis in human K562 cells assessed as early apoptotic cells at 5 uM incubated for 48 hrs by Annexin V-FITC/PI staining based flow cytometry analysis (Rvb= 16.26%) | Homo sapiens | 1 | ALA5113400 | cell-based format | Scientific Literature | |
| 18. | ALA5115354 | F | Induction of apoptosis in human K562 cells assessed as early apoptotic cells at 10 uM incubated for 48 hrs by Annexin V-FITC/PI staining based flow cytometry analysis (Rvb= 16.26%) | Homo sapiens | 1 | ALA5113400 | cell-based format | Scientific Literature | |
| 19. | ALA5115355 | F | Induction of apoptosis in human K562 cells assessed as late apoptotic cells at 1 uM incubated for 48 hrs by Annexin V-FITC/PI staining based flow cytometry analysis (Rvb= 2.89%) | Homo sapiens | 1 | ALA5113400 | cell-based format | Scientific Literature | |
| 20. | ALA5115356 | F | Induction of apoptosis in human K562 cells assessed as late apoptotic cells at 5 uM incubated for 48 hrs by Annexin V-FITC/PI staining based flow cytometry analysis (Rvb= 2.89%) | Homo sapiens | 1 | ALA5113400 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!