#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA5148372	Binding	Displacement of conivaptan-red from SNAP-tagged human V2 receptor expressed in HEK293 cells measured after 1 hr by HTRF assay	Homo sapiens	22	ALA5143707	cell-based format	Scientific Literature
2.	ALA5148374	Binding	Displacement of [3H]-vasopressin from human V1A receptor expressed in CHO cells membrane by microbeta scintillation counter analysis	Homo sapiens	2	ALA5143707	cell membrane format	Scientific Literature
3.	ALA5148375	Functional	Antagonist activity at human V2 receptor expressed in CHO cells assessed as inhibition of vasopressin-induced cAMP accumulation incubated for 1 hr	Homo sapiens	2	ALA5143707	cell-based format	Scientific Literature
4.	ALA5148376	Functional	Inverse agonist activity at human V2 receptor expressed in CHO cells assessed as reduction in basal cAMP level incubated for 1 hr	Homo sapiens	2	ALA5143707	cell-based format	Scientific Literature
5.	ALA5148377	Functional	Inhibition of cyst formation in MDCK cells at 1 uM treated for 8 consecutive days	Canis lupus familiaris	2	ALA5143707	cell-based format	Scientific Literature
6.	ALA5148378	Functional	Inhibition of cyst formation in MDCK cells at 1 to 10 uM	Canis lupus familiaris	1	ALA5143707	cell-based format	Scientific Literature
7.	ALA5148379	Functional	Inhibition of cyst formation in MDCK cells treated on day 4 and measured from day 6	Canis lupus familiaris	1	ALA5143707	cell-based format	Scientific Literature
8.	ALA5148380	Functional	Suppression of renal cyst development in embryonic kidney of 8-Br-cAMP induced wild type C57BL/6 mouse model of autosomal dominant polycystic kidney disease measured after 8 days by inverted microscopic analysis	Mus musculus	1	ALA5143707	organism-based format	Scientific Literature
9.	ALA5148381	Functional	Suppression of renal cyst development in Pkd1 flox/flox;Ksp-Cre mouse model of autosomal dominant polycystic kidney disease assessed as reduction in kidney size at 5 mg/kg, sc administered once daily starting from postnatal day 6 to 12 days	Mus musculus	2	ALA5143707	organism-based format	Scientific Literature
10.	ALA5148382	Functional	Suppression of renal cyst development in Pkd1 flox/flox;Ksp-Cre mouse model of autosomal dominant polycystic kidney disease assessed as reduction in renal cystic index at 5 mg/kg, sc administered once daily starting from postnatal day 6 to 12 days (Rvb = 23 +/- 1 %)	Mus musculus	2	ALA5143707	organism-based format	Scientific Literature
11.	ALA5148383	Functional	Suppression of renal cyst development in Pkd1 flox/flox;Ksp-Cre mouse model of autosomal dominant polycystic kidney disease assessed as increase in body weight at 5 mg/kg, sc administered once daily starting from postnatal day 6 to 12 days	Mus musculus	2	ALA5143707	organism-based format	Scientific Literature
12.	ALA5148384	Functional	Suppression of renal cyst development in Pkd1 flox/flox;Ksp-Cre mouse model of autosomal dominant polycystic kidney disease assessed as reduction in kidney size at 5 mg/kg, sc administered once daily starting from postnatal day 6 to 12 days by hematoxylin and eosin staining based assay	Mus musculus	2	ALA5143707	organism-based format	Scientific Literature
13.	ALA5148385	Functional	Suppression of renal cyst development in Pkd1 flox/flox;Ksp-Cre mouse model of autosomal dominant polycystic kidney disease assessed as reduction in cyst formation at 5 mg/kg, sc administered once daily starting from postnatal day 6 to 12 days by hematoxylin and eosin staining based assay	Mus musculus	2	ALA5143707	organism-based format	Scientific Literature
14.	ALA5148386	Toxicity	Toxicity in wild type C57BL/6 mouse assessed as change in kidney size at 5 mg/kg, sc administered once daily starting from postnatal day 6 to 12 days	Mus musculus	2	ALA5143707	organism-based format	Scientific Literature
15.	ALA5148387	Toxicity	Toxicity in wild type C57BL/6 mouse assessed as change in body weight at 5 mg/kg, sc administered once daily starting from postnatal day 6 to 12 days	Mus musculus	2	ALA5143707	organism-based format	Scientific Literature
16.	ALA5148388	Binding	Selectivity index, ratio of Ki for human V2R expressed in HEK293 cells to Ki for human V1AR expressed in CHO cells	Homo sapiens	2	ALA5143707	cell-based format	Scientific Literature
17.	ALA5148389	ADME	AUC (0 to last) in C57BL/6 mouse at 5 mg/kg, sc measured upto 8 hrs by LC-MS analysis	Mus musculus	1	ALA5143707	organism-based format	Scientific Literature
18.	ALA5148390	ADME	Cmax in C57BL/6 mouse at 5 mg/kg, sc measured upto 8 hrs by LC-MS analysis	Mus musculus	1	ALA5143707	organism-based format	Scientific Literature
19.	ALA5148391	ADME	Half life in C57BL/6 mouse at 5 mg/kg, sc measured upto 8 hrs by LC-MS analysis	Mus musculus	1	ALA5143707	organism-based format	Scientific Literature
20.	ALA5148392	ADME	Drug concentration in kidney of C57BL/6 mouse at 5 mg/kg, sc measured at 0.5 hr by HPLC analysis	Mus musculus	2	ALA5143707	organism-based format	Scientific Literature