# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5154013 | F | Antagonist activity at CCR5 (unknown origin) expressed in HEK293 cells co-expressing Galpha16 assessed as intracellular calcium change incubated for 15 mins by Fluo-4 AM calcium flux assay | Homo sapiens | 23 | cell-based format | Scientific Literature | ||
2. | ALA5154014 | F | Antiviral activity against HIV-1 Ba-L infected in human TZM-bl cells measured after 48 hrs incubation by luciferase based analysis | Human immunodeficiency virus 1 | 16 | organism-based format | Scientific Literature | ||
3. | ALA5154015 | T | Cytotoxicity against human TZM-bl cells incubated for 48 hrs by MTT assay | Homo sapiens | 22 | cell-based format | Scientific Literature | ||
4. | ALA5154016 | T | Therapeutic index, ratio of CC50 for human TZM-bl cells to EC50 for antiviral activity against HIV-1 Ba-L | 15 | assay format | Scientific Literature | |||
5. | ALA5154017 | T | Cytotoxicity against human PM1 cells incubated for 48 hrs by MTT assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
6. | ALA5154018 | T | Cytotoxicity against human HOS-CD4-CCR5 cells incubated for 48 hrs by MTT assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
7. | ALA5154019 | T | Cytotoxicity against human PBMC cells incubated for 48 hrs by MTT assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
8. | ALA5154020 | F | Antiviral activity against HIV-1 SF162 infected in human TZM-bl cells measured after 48 hrs incubation by luciferase based analysis | Human immunodeficiency virus 1 | 6 | organism-based format | Scientific Literature | ||
9. | ALA5154021 | F | Antiviral activity against HIV-1 YU-2 infected in human TZM-bl cells measured after 48 hrs incubation by luciferase based analysis | Human immunodeficiency virus 1 | 6 | organism-based format | Scientific Literature | ||
10. | ALA5154022 | F | Antiviral activity against HIV-1 Ba-L infected in human HOS-CD4-CCR5 cells measured after 48 hrs incubation by ELISA based p24 antigen assay | Human immunodeficiency virus 1 | 3 | organism-based format | Scientific Literature | ||
11. | ALA5154023 | T | Therapeutic index, ratio of CC50 for human HOS-CD4-CCR5 cells to EC50 for antiviral activity against HIV-1 Ba-L | 3 | assay format | Scientific Literature | |||
12. | ALA5154024 | F | Antiviral activity against HIV-1 Ba-L infected in human PM1 cells measured after 48 hrs incubation by ELISA based p24 antigen assay | Human immunodeficiency virus 1 | 3 | organism-based format | Scientific Literature | ||
13. | ALA5154025 | T | Therapeutic index, ratio of CC50 for human PM1 cells to EC50 for antiviral activity against HIV-1 Ba-L | 3 | assay format | Scientific Literature | |||
14. | ALA5154026 | T | Therapeutic index, ratio of CC50 for human PM1 cells to EC50 for antiviral activity against HIV-1 YU-2 | 3 | assay format | Scientific Literature | |||
15. | ALA5154027 | T | Therapeutic index, ratio of CC50 for human PM1 cells to EC50 for antiviral activity against HIV-1 SF162 | 3 | assay format | Scientific Literature | |||
16. | ALA5154028 | F | Antiviral activity against HIV-1 IIIB infected in human TZM-bl cells measured after 48 hrs incubation by luciferase based analysis | Human immunodeficiency virus 1 | 3 | organism-based format | Scientific Literature | ||
17. | ALA5154029 | F | Antiviral activity against HIV-1 KM018 clinical isolate infected in human PBMC measured after 48 hrs incubation by luciferase based analysis | Human immunodeficiency virus 1 | 3 | organism-based format | Scientific Literature | ||
18. | ALA5154030 | T | Therapeutic index, ratio of CC50 for human PBMC to EC50 for antiviral activity against HIV-1 KM018 clinical isolate | 3 | assay format | Scientific Literature | |||
19. | ALA5154031 | F | Antiviral activity against HIV-1 KIZ001 clinical isolate infected in human PBMC measured after 48 hrs incubation by luciferase based analysis | Human immunodeficiency virus 1 | 3 | organism-based format | Scientific Literature | ||
20. | ALA5154032 | T | Therapeutic index, ratio of CC50 for human PBMC to EC50 for antiviral activity against HIV-1 KIZ001 clinical isolate | 3 | assay format | Scientific Literature |