| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5108175 | T | Cytotoxicity against mouse L929 cells assessed as cell growth inhibition incubated for 72 hrs by MTT assay | Mus musculus | 49 | cell-based format | Scientific Literature | ||
| 2. | ALA5108176 | F | Cytotoxicity against human HCT-116 cells assessed as cell growth inhibition incubated for 72 hrs by MTT assay | Homo sapiens | 50 | cell-based format | Scientific Literature | ||
| 3. | ALA5108177 | F | Cytotoxicity against human PC-3 cells assessed as cell growth inhibition incubated for 72 hrs by MTT assay | Homo sapiens | 50 | cell-based format | Scientific Literature | ||
| 4. | ALA5108178 | F | Cytotoxicity against human HL-60 cells assessed as cell growth inhibition incubated for 72 hrs by MTT assay | Homo sapiens | 50 | cell-based format | Scientific Literature | ||
| 5. | ALA5108179 | F | Cytotoxicity against human SNB-19 cells assessed as cell growth inhibition incubated for 72 hrs by MTT assay | Homo sapiens | 50 | cell-based format | Scientific Literature | ||
| 6. | ALA5108180 | T | Selectivity index, ratio of IC50 for cytotoxicity against mouse L929 cells to IC50 for cytotoxicity against human HCT-116 cells | 45 | cell-based format | Scientific Literature | |||
| 7. | ALA5108181 | T | Selectivity index, ratio of IC50 for cytotoxicity against mouse L929 cells to IC50 for cytotoxicity against human PC-3 cells | 45 | cell-based format | Scientific Literature | |||
| 8. | ALA5108182 | T | Selectivity index, ratio of IC50 for cytotoxicity against mouse L929 cells to IC50 for cytotoxicity against human HL-60 cells | 45 | cell-based format | Scientific Literature | |||
| 9. | ALA5108183 | T | Selectivity index, ratio of IC50 for cytotoxicity against mouse L929 cells to IC50 for cytotoxicity against human SNB-19 cells | 45 | cell-based format | Scientific Literature | |||
| 10. | ALA5108184 | F | Induction of cell membrane integrity loss in human HCT-116 cells assessed as reduction in number of viable cells at 0.85 to 3.5 uM incubated for 24 hrs by propidium iodide staining based flow cytometry | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA5108185 | F | Induction of apoptosis in human HCT-116 cells at 1.7 uM incubated for 24 hrs by Annexin V/7-AAD staining based flow cytometry | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA5108186 | F | Induction of apoptosis in human HCT-116 cells at 3.5 uM incubated for 24 hrs by Annexin V/7-AAD staining based flow cytometry | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA5108187 | F | Induction of mitochondrial membrane potential depolarization in human HCT-116 cells at 0.85 to 3.5 uM incubated for 24 hrs by Rhodamine 123 based flow cytometry | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA5108188 | F | Induction of apoptosis in human HCT-116 cells assessed as increase in intracellular ROS level at 1.7 to 3.5 uM incubated for 5 hrs by CM-H2DCFDA staining based flow cytometry | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA5108189 | F | Induction of apoptosis in human HCT-116 cells assessed as increase in intracellular ROS level at 1.7 to 3.5 uM incubated for 1 to 5 hrs by CM-H2DCFDA staining based flow cytometry | Homo sapiens | 1 | cell-based format | Scientific Literature |
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